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http://dx.doi.org/10.1093/eurheartj/ehae899 | DOI Listing |
PLoS Biol
January 2025
School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
The organization of the human genome in space and time is critical for transcriptional regulation and cell fate determination. However, robust methods for tracking genome organization or genomic interactions over time in living cells are lacking. Here, we developed a multicolor DNA labeling system, ParSite, to simultaneously track triple genomic loci in the U2OS cells.
View Article and Find Full Text PDFPLoS One
January 2025
Management School, Harbin University of Commerce, Harbin, Heilongjiang, China.
Road traffic congestion on the cold chain logistics not only increase the cost and time, but also creates certain negative impact on the national carbon emissions. To fully utilize the traffic resources, this study has classified urban road traffic congestion and defined the various vehicle delivery speeds with dynamic congestion levels. Simultaneously, it has developed the cold chain products replenishment strategy by considering delivery route, multi-depot condition and even vehicle types, aiming to minimize the total cost and carbon emissions, and maximizing the cold chain products freshness.
View Article and Find Full Text PDFPLoS One
January 2025
School of Public Health, University of Memphis, Memphis, Tennessee, United States of America.
Female Genital Mutilation (FGM) has become a global health concern. It is a deeply entrenched harmful practice involving partial or total removal of the external female genitalia for non-medical reasons. To inform effective policymaking and raise awareness about FGM's health risks, understanding socioeconomic and demographic factors influencing the timing of girls' circumcision is crucial.
View Article and Find Full Text PDFDatabase (Oxford)
January 2025
Division of Agricultural Bioinformatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi 110012, India.
Amidst the global challenge of extreme poverty, the livestock sector can significantly contribute to global sustainable development goals by enhancing resilience, smallholder productivity, and market participation. The Indian livestock sector is one of the largest in the world with a total livestock population of 535.82 million, ∼10.
View Article and Find Full Text PDFBiometrics
January 2025
Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, United States.
Distributed lag models (DLMs) estimate the health effects of exposure over multiple time lags prior to the outcome and are widely used in time series studies. Applying DLMs to retrospective cohort studies is challenging due to inconsistent lengths of exposure history across participants, which is common when using electronic health record databases. A standard approach is to define subcohorts of individuals with some minimum exposure history, but this limits power and may amplify selection bias.
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