The data of 764 patients, registered with the Netherlands Committee for Testicular Tumors during the 1971-1978 period, were analyzed. To a large degree the results were in agreement with those in the literature. Chest x-rays and bipedal lymphangiograms were the most useful investigations for detection of metastases, with supplementation by lung planigraphy where indicated. Local invasion of extratesticular tissue by tumor had no relationship to prognosis. The survival figures were comparable to those of the better series in the literature. There was essentially no difference between the behavior and treatment of combined tumors and malignant teratomas, so these may be viewed as a single entity. Because recurrences occurred after 2 years in 21% of seminoma patients, and in 4% of nonseminoma patients, a minimum follow-up period of 5 years is desirable.
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http://dx.doi.org/10.1002/1097-0142(19850401)55:7<1612::aid-cncr2820550734>3.0.co;2-b | DOI Listing |
Urol Case Rep
January 2025
Faculty member, Faculty of Medicine, Pathology Department, Damascus University, Damascus, Syrian Arab Republic.
Leydig cell tumors (LCTs) are rare testicular neoplasms, representing 1-3% of all testicular tumors. A 65-year-old male presented with a painless left scrotal mass. Ultrasound revealed a 61 × 53 × 35 mm tumor with heterogeneous echogenicity and abundant blood supply.
View Article and Find Full Text PDFUrology
January 2025
Department of Urology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address:
This review examines the historical evolution of testicular cancer (TCa) treatment, emphasizing the transformative impact of World War II. Prior to the war, cases of more than 50 testicular tumors were exceedingly rare. The mobilization of American troops, especially after the German Blitz, resulted in widespread military health screenings, leading to a surge in incidental TCa diagnoses during the 1940s.
View Article and Find Full Text PDFJ Hematop
January 2025
Mayo Clinic, Rochester, MN, USA.
Testicular follicular lymphoma (TFL) is an exceedingly rare lymphoma that typically occurs in young male patients and is now recognized as a distinct diagnostic entity in the International Consensus Classification. TFL shows some clinicopathologic and genetic overlap with pediatric-type follicular lymphoma (PTFL). We report a case of TFL occurring in an otherwise healthy 4-year-old boy who presented with painless scrotal swelling.
View Article and Find Full Text PDFEur Radiol
January 2025
Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
Objectives: The Scrotal and Penile Imaging Working Group (SPIWG) of the European Society of Urogenital Radiology (ESUR) aimed to formulate recommendations on the imaging modalities and minimal technical requirements for abdominopelvic imaging in the follow-up of adult patients treated for testicular germ-cell tumors (TGCT).
Methods: The SPIWG members performed an extensive literature search, reviewed the current clinical practice, and reached a consensus based on the opinions of experts in the field.
Results: Recurrence in patients treated for TGCT mainly occurs in retroperitoneal lymph nodes (LNs).
Animals (Basel)
January 2025
Department of Biology, University of Naples Federico II, 80126 Naples, Italy.
Transferrin Receptor 2 (TfR2) is a homolog of Transferrin Receptor 1 (TfR1), involved in regulating intra and extracellular iron levels. Altered iron pathways have been associated with cancer onset and progression; however, their role in canine tumors remains poorly explored. This study investigated TfR2 immunohistochemical expression in non-neoplastic canine testis for the first time and in the most common types of canine testicular tumors: intratubular seminomas (ITSEMs), diffuse seminomas (DSEMs), Leydig cell tumors (LCTs), and Sertoli cell tumors (SCTs).
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