Background: While two-thirds of the 57 million people with dementia worldwide live in low- and middle-income countries, research to inform dementia-related policy in these regions remains scarce. We aimed to increase early dementia diagnosis and the use of standardized cognitive assessment by PCP in primary care settings in Cuba METHOD: We selected 16 Primary care clinics, with an estimated 160-200 providers. Clinics were carefully paired based on a number of providers, population demographics, and baseline rates of cognitive impairment diagnosis before being randomized into two groups: one to receive a targeted intervention and the other to continue with usual care practices. The target intervention included a dementia training program and methods for cognitive assessment. A questionnaire about attitudes and practices towards the use of technology-screening tools, diagnosis, and management of cognitive impairment in primary care was applied to GP at the beginning of the study, 6 months and 12 after training course. The primary endpoint was change in dementia diagnosis rates 12 months after the target intervention.
Result: Compared with the usual care group, the intervention group showed significant statistical improvement in the level of confidence in their ability to engage in key aspects of the neurocognitive evaluation, perform memory screening in older people during annual health visits, and confidence during cognitive evaluation. In addition, the intervention group showed significant improvement in interpreting the diagnostic test (χ² = 8.022; p-value = 0.004), selecting which test is appropriate (χ² = 10.756; p-value = 0.001) and familiarity with diagnostic criteria for different forms of dementia. In the intervention group, the frequency of PCP cognitive diagnoses (primary outcome) and referrals to memory specialists increase by 141% relative to baseline, and the use of standardized cognitive assessment for annual cognitive evaluation increased by 83%. The overall prevalence of dementia at selected primary care clinics was 10.6% (95% CI, 9.3%-12.8%).
Conclusion: This study confirms the feasibility of training primary care physicians (PCPs) for the early detection, treatment, and support of individuals with dementia and their families.
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http://dx.doi.org/10.1002/alz.086012 | DOI Listing |
BMC Psychol
January 2025
Department of Midwifery, University of West Attica, Athens, Greece.
Background: The increasing awareness of the emotional consequences of emergency cesarean deliveries (C-sections) highlights their substantial role in fostering postpartum post-traumatic stress disorder (PTSD). This systematic review and meta-analysis aim to evaluate the prevalence and determinants of PTSD following emergency C-sections, as well as the implications of these events on maternal mental health and welfare.
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Skelet Muscle
January 2025
Department of Molecular Physiology and Biophysics, and Department of Neurology, Howard Hughes Medical Institute, Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
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View Article and Find Full Text PDFCell Biosci
January 2025
State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200438, People's Republic of China.
Background: Neuropathic pain resulting from spinal cord injury (SCI) is associated with persistent hyperactivity of primary nociceptors. Anandamide (AEA) has been reported to modulate neuronal excitability and synaptic transmission through activation of cannabinoid type-1 receptors (CB1Rs) and transient receptor potential vanilloid 1 (TRPV1). However, the role of AEA and these receptors in the hyperactivity of nociceptors after SCI remains unclear.
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January 2025
School of Public Health, Lanzhou University, Lanzhou, Gansu, China.
Background: China has always been a country with a high burden of tuberculosis. In order to end TB, the Chinese government launched three plans for TB prevention and control. The Chinese government implemented the National 13th Five-Year plan for Tuberculosis Prevention and Control (2016-2020) to promote TB prevention and control from policy, technology, health promotion and other aspects from 2016 to 2020.
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January 2025
Department of Clinical Pharmacology and Evidence-Based Medicine, NCJSC "Karaganda Medical University", 40, Gogolya St, Karaganda, 100000, Kazakhstan.
Background: Kazakhstan inherited the Semashko health system model, known for the centralized adoption of rules at the Ministry of Health (MoH) level that regulate the healthcare system. In 2019 MoH established a national framework with indicators aimed at collecting qualitative and quantitative data from healthcare organizations as part of their annual self-evaluation, and biannual external evaluation by the National Research Center for Health Development (NRCHD). The purpose of this study was to pilot the MoH framework on rational use of medicines and evaluate its effects on medicine use practices in health care organizations and at the national level.
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