Background: Existing evidence supports that living in a friendly environment is associated with lower risk of dementia, although the measurements of environmental variables are mixed. However, the type of environmental features reducing dementia risk has not been comprehensively identified and such associations have not been quantified. This systematic review and meta-analysis aims to summarize the objectively measured environmental features associated with dementia and examine the pooled association between those features and dementia risk in older adults.
Method: We systematically searched PubMed, Web of Science, and EBSCO (Abstracts in Social Gerontology, AgeLine, APA PsycINFO, and CINAHL) databases on December 21, 2023, to identify the empirical studies assessing the role of objectively measured environmental features in the risk of dementia. The search yielded a total of 890 citations. According to the inclusion and exclusion criteria, ten studies were included in the systematic review and meta-analysis. Among them, four articles included more than one environmental features, resulting in a total of 15 associations between environmental variables and dementia risk.
Result: This study summaries five environmental features that have been reported to be associated with lower dementia risk, including longer distance between residence and major roads (Hazard Ratio [HR] = 0.94, 95% Confidence Interval[CI] = 0.88-1.00), larger green space (HR = 0.94, 95%CI = 0.88-1.00), higher level of sidewalk installation (HR = 0.71, 95%CI = 0.52-0.90), and less exposure to air pollution (i.e., NO2 [HR = 1.05, 95%CI = 0.96-1.15], PM2.5 [HR = 1.03, 95%CI = 1.02-1.05], and PM10 [HR = 1.13, 95%CI = 1.05-1.21]). Pooled analysis showed that living in a friendly environment may reduce 7% of the risk of dementia (HR = 0.93, 95%CI = 0.90-0.97) and exposure to air pollution may increase 5% of the dementia risk (HR = 1.05, 95%CI = 1.02-1.08). There was heterogeneity in results across studies.
Conclusion: Even though a small number of studies included in this systematic review and meta-analysis have examined the association between objectively measured environmental features and dementia risk, all existing investigations point to statistically significant associations in older adults. Whether those associations vary in different population subgroups and the mechanisms underlying those associations warrant further investigation.
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http://dx.doi.org/10.1002/alz.091425 | DOI Listing |
Sci Rep
January 2025
College of Geography and Planning, Chengdu University of Technology, Chengdu, 610059, China.
The natural suitability of human settlements is greatly influenced by the distinct ecological environment and natural conditions of the plateau area, which are of great eco-environmental significance. 32 counties in China's Western Sichuan Plateau were chosen as the study's research subjects. The evaluation index system and weight of the natural suitability of human settlements were established, along with the obstacle degree model, using the analytical hierarchy process, the entropy method, and the integrated weight method.
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January 2025
Pesticide Formulation Research Department, Central Agriculture Pesticides Laboratory, Agricultural Research Center, Alexandria, Egypt.
Formulation and adjuvant technologies can facilitate the use of insecticides that have higher biological efficiency application features. Safety, physicochemical properties by increasing consumer demand for safe food and enhancing operator safety. The aim of this current work was to develop a green efficient, and stable pesticide formulation.
View Article and Find Full Text PDFThe paper introduces a method for predicting damage intensity in masonry residential buildings situated in mining areas, focusing on the impact of large-scale continuous ground deformation. The research utilizes in situ data collected in a database, encompassing structural and material features, as well as information on maintenance quality and building durability. In addition to this information, the database collected data on the intensity of continuous deformation of the mining area at the location of the building, as well as the range and intensity of damage identified in buildings.
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January 2025
Department of Computer Engineering, Inha University, Incheon, Republic of Korea.
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas.
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January 2025
Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
The integration of radar technology into smart furniture represents a practical approach to health monitoring, circumventing the concerns regarding user convenience and privacy often encountered by conventional smart home systems. Radar technology's inherent non-contact methodology, privacy-preserving features, adaptability to diverse environmental conditions, and high precision characteristics collectively establish it a compelling alternative for comprehensive health monitoring within domestic environments. In this paper, we introduce a millimeter (mm)-wave radar system positioned strategically behind a seat, featuring an algorithm capable of identifying unique cardiac waveform patterns for healthy subjects.
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