Background: Most assisted living (AL) settings organize and provide opportunities for residents to participate in activities (e.g., exercise, music, arts and craft, cognitive activities, religious services, community outings). Despite the known benefits of activity participation, it is widely reported that there is a lack of activities that are considered meaningful for residents and thus many residents spend much of their time during the day disengaged. Further, there are numerous challenges to engaging assisted living (AL) residents with dementia in meaningful activity at the resident and community level. Resident challenges include acute medical events, advanced age, comorbidities, physical and cognitive abilities, lack of motivation, cultural expectations, pain, and behavioral symptoms of distress (BSD). Community level challenges include environments and policies that limit opportunities for meaningful activities and limited resources.
Method: To overcome these challenges and optimize engagement in meaningful activity for residents with dementia, the Meaningful Activity for Managing Behavioral Symptoms of Distress (MAC-4-BSD) intervention was developed. MAC-4-BSD is theoretically based using the Social Ecological Model and Social Cognitive Theory and includes four components: 1. Assessment of the environment and policies; 2. Education of staff; 3. Assessment of resident preferences and goals for meaningful activity; 4. Mentoring and motivating staff and residents. The overall aim of MAC-4-BSD is to reduce BSD, increase engagement in meaningful activity, and improve quality of life for residents by modifying the environment and empowering staff to facilitate and engage residents with dementia in AL settings. The MAC-4-BSD intervention is implemented by a Research Facilitator working with a facility champion and monthly meetings take place with a facility stakeholder team to provide updates on successful strategies and brainstorm challenges encountered.
Results: To date, a total of 5 AL settings and 71 residents with dementia have participated in the study. Based on content analysis of field notes we will describe stakeholder goals established, barriers to implementation, and facilitators to meet goals in the participating settings.
Conclusions: Key findings include the influence of administrative or leadership support, level of engagement among direct care staff, interdisciplinary collaboration, and access to resources and supplies in the environment to facilitate meaningful activity for residents with dementia.
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http://dx.doi.org/10.1002/alz.086604 | DOI Listing |
Background: Clinical outcome assessments (COAs) that measure functional capacities are key tools to evaluate efficacy in Alzheimer's disease (AD) clinical trials. The Alzheimer's Disease Cooperative Study Activities of Daily Living (ADCS-ADL) scale is frequently used to assess changes in both basic and instrumental activities of daily living, but there is no clear consensus on what magnitude of change on this scale may be considered clinically meaningful. To address this question, we conducted anchor-based analyses (as recommended by the FDA) to explore meaningful within-patient/participant change thresholds on the ADCS-ADL.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Preclinical Alzheimer's disease (AD) trials can involve multiple years of follow-up and burdensome procedures for older individuals. Optimizing the design and conduct of these trials requires input from participants and their families. Since 2020, the Alzheimer's Clinical Trials Consortium (ACTC) Research Participant Advisory Board has provided input on study attributes including: participant and study partner compensation, consent language, and result communication tools.
View Article and Find Full Text PDFBackground: Understanding the fundamental differences between the human and pre-human brain is a prerequisite for designing meaningful models and therapies for AD. Expressed CHRFAM7A, a human restricted gene with carrier frequency of 75% in the human population predicts profound translational significance.
Method: The physiological role of CHRFAM7A in human brain is explored using multiomics approach on 600 post mortem human brain tissue samples (ROSMAP).
Alzheimers Dement
December 2024
Faculty of Health, University of Canberra, Bruce, ACT, Australia.
Background: There is a need to understand the benefits and limitations of innovative models of dementia care to ensure models meet the needs of people living with dementia, their families and staff. The aim of this scoping review was to explore and synthesise the barriers and facilitators to the widespread implementation of small-scale residential dementia care.
Method: A scoping review was conducted in 2023 in MEDLINE, CINAHL, PsycINFO, Scopus, Web of Science, and CENTRAL to identify empirical, peer-reviewed studies, published in English from database inception to October 2023.
Alzheimers Dement
December 2024
Stevenson University, Owings Mills, MD, USA.
Background: Most assisted living (AL) settings organize and provide opportunities for residents to participate in activities (e.g., exercise, music, arts and craft, cognitive activities, religious services, community outings).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!