Background: Sundowning is the development or progression of neuropsychiatric symptoms (NPS) often occurring in the afternoon or early evening. Noninvasive ambient sensors (NAS) monitor individuals without the need to wear a device or use a camera. The data from NAS sensors can identify movement patterns in the context of cyclomatic complexity to indicate when an individual may be sundowning. This approach could improve the quality of life (QOL) for individuals with Alzheimer's disease (AD) and their caregivers.
Method: NAS sensors placed in an individual's home could identify wandering due to sundowning when new patterns of movement emerge. Quantification of movement with cyclomatic complexity uses machine learning (ML) to identify and notify caregivers when new sequences of room transitions emerge. Cyclomatic complexity is represented as M = E - N + 2P where E is the amount of walking paths, N is the number of rooms, P is the total number of connected rooms (Khan & Jacobs). A new pattern of movement categorized as wandering is one signal a caregiver could consider within the constellation of symptoms.
Result: The method of approaching quantification of movement in an ML framework was pioneered by Dr. Taha Khan and Dr. Peter G. Jacobs in the study "Prediction of Mild Cognitive Impairment Using Movement Complexity". Labeling sequences of human movement within an ML framework could lead to novel insights for understanding human behavior. Individuals that prefer to age-in-place could benefit from early detection of neuropsychiatric symptoms and prevention of sentinel events with proactive clinical decision-making.
Conclusion: The transition from CIN to MCI is a significant change for an individual. Current assessments are dependent on the clinical interpretation by the caregiver. Instead of waiting until a sentinel event occurs, predictive algorithms could be used for early intervention. Data could enhance the decision making-support for further assessment or admission to a long-term care facility. As the aging population continues to grow, affordable technological solutions will be critical for monitoring health factors in real-time. By providing this early warning, caregivers can adjust their routines and interventions to better support the patient.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/alz.091052 | DOI Listing |
Alzheimers Dement
December 2024
WellBe Senior Medical, Atlanta, GA, USA.
Background: Patterns of human movement evolve as an individual experiences the progression from cognitively intact (CIN) to mild cognitive impairment (MCI) and finally dementia and Alzheimer's Disease (AD). Quantification of movement with the goal of identifying MCI though step counts alone do not take into consideration the floor layout of a home. Cyclomatic complexity is an approach to normalizing differences in the individual's living space to better predict the transition from CIN to MCI.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
WellBe Senior Medical, Atlanta, GA, USA.
Background: Sundowning is the development or progression of neuropsychiatric symptoms (NPS) often occurring in the afternoon or early evening. Noninvasive ambient sensors (NAS) monitor individuals without the need to wear a device or use a camera. The data from NAS sensors can identify movement patterns in the context of cyclomatic complexity to indicate when an individual may be sundowning.
View Article and Find Full Text PDFSci Total Environ
December 2024
Drug Theoretics and Cheminformatics (DTC) Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India. Electronic address:
Sci Rep
September 2023
Department of Materials Science and Engineering, Delft University of Technology, 2628 CD, Delft, The Netherlands.
Technological processes, reconstructed from the archaeological record, are used to study the evolution of behaviour and cognition of Neanderthals and early modern humans. In comparisons, technologies that are more complex infer more complex behaviour and cognition. The manufacture of birch bark tar adhesives is regarded as particularly telling and often features in debates about Neanderthal cognition.
View Article and Find Full Text PDFMacromolecules
March 2022
Istituto per le Applicazioni del Calcolo CNR, Via dei Taurini 19, 00185 Rome, Italy.
Photocurable polymers are used ubiquitously in 3D printing, coatings, adhesives, and composite fillers. In the present work, the free radical polymerization of photocurable compounds is studied using reactive classical molecular dynamics combined with a dynamical approach of the nonequilibrium molecular dynamics (D-NEMD). Different concentrations of radicals and reaction velocities are considered.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!