In this article, we examine the pros and cons of textbook vs. journal articles. We suggest that textbooks serve as an essential knowledge provider for colleagues, especially at their entry level, but to advance clinical and academic capability, journal articles remain an important and unreplaceable tool for continuous professional development. Currently multi-author review articles provide one of the best sources of information, providing recommendations that are authoritative yet balanced. We explored if there are options to combine the best of both these platforms of information.
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http://dx.doi.org/10.1177/17531934241307497 | DOI Listing |
Animal Model Exp Med
January 2025
Guangdong Medical Laboratory Animal Center, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Background: Makorin ring finger protein 3 gene (MKRN3) gene mutation is the most common genetic cause of central precocious puberty (CPP) in children. Due to the lack of ideal MKRN3-modified animal model (MKRN3-modified mice enter puberty only 4-5 days earlier than normal mice), the related research is limited.
Methods: Therefore, the MKRN3-modified rabbit was developed using CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technology.
Am J Hum Biol
January 2025
One Health Research Group, Universidad de Las Américas, Quito, Ecuador.
Background: The misalignment of sleeping times during weekdays/weekends (i.e., social jetlag) is particularly common among adolescents and plausibly associated with their physical fitness.
View Article and Find Full Text PDFJ Cardiovasc Electrophysiol
January 2025
TriHealth Heart & Vascular Institute, Cincinnati, Ohio, USA.
Introduction: A leadless pacemaker (LLPM) was recommended for a patient with intermittent complete heart block and near-syncope.
Methods And Results: Delivery of LLPM is through a large sheath that has limited deflection and steerability. This report describes the successful deployment of a ventricular LLPM in a patient with prior surgical correction of AV septal defect with subsequent significant right atrial enlargement.
Animal Model Exp Med
January 2025
Cancer Institute, School of Medicine, Jianghan University, Wuhan, China.
The high morbidity and mortality of colorectal cancer (CRC) is a major challenge in clinical practice. Although a series of alternative research models of CRC have been developed, appropriate orthotopic animal models that reproduce the specific clinical response as well as pathophysiological immune features of CRC are still lacking. In the current study, we constructed a CRC orthotopic xenograft model by implanting the tumor tubes at the colorectum of mice and monitored the model development using bioluminescence imaging.
View Article and Find Full Text PDFActa Physiol (Oxf)
February 2025
Zoophysiology, Department of Biology, Aarhus University, Aarhus C, Denmark.
Aim: Snakes exhibit remarkable physiological shifts when their large meals induce robust postprandial growth after prolonged fasting. To understand the regulatory mechanisms underlying this rapid metabolic transition, we examined the regulation of protein synthesis in pythons, focusing on processes driving early postprandial tissue remodeling and growth.
Methods: Using the SUnSET method with puromycin labeling, we measured in vivo protein synthesis in fasting and digesting snakes at multiple post-feeding intervals.
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