Objective: To establish local diagnostic reference levels (DRLs) for pediatric neck CT based on age, weight, and water-equivalent diameter (WED) across multiple university hospitals in South Korea.
Materials And Methods: This retrospective study analyzed pediatric neck CT examinations from nine university hospitals, involving patients aged 0-18 years. Data were categorized by age, weight, and WED, and radiation dose metrics, including volume CT dose index (CTDI) and dose length product, were recorded. Data retrieval and analysis were conducted using a commercially available dose-management system (Radimetrics, Bayer Healthcare). Local DRLs were established following the International Commission on Radiological Protection guidelines, using the 75th percentile as the reference value.
Results: A total of 1159 CT examinations were analyzed, including 169 scans from Institution 1, 132 from Institution 2, 126 from Institution 3, 129 from Institution 4, 128 from Institution 5, 105 from Institution 6, 162 from Institution 7, 127 from Institution 8, and 81 from Institution 9. Radiation dose metrics increased with age, weight, and WED, showing significant variability both within and across institutions. For patients weighing less than 10 kg, the DRL for CTDI was 5.2 mGy. In the 10-19 kg group, the DRL was 5.8 mGy; in the 20-39 kg group, 7.6 mGy; in the 40-59 kg group, 11.0 mGy; and for patients weighing 60 kg or more, 16.2 mGy. DRLs for CTDI by age groups were as follows: 5.3 mGy for infants under 1 year, 5.7 mGy for children aged 1-4 years, 7.6 mGy for ages 5-9 years, 11.2 mGy for ages 10-14 years, and 15.6 mGy for patients 15 years or older.
Conclusion: Local DRLs for pediatric neck CT were established based on age, weight, and WED across nine university hospitals in South Korea.
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http://dx.doi.org/10.3348/kjr.2024.0689 | DOI Listing |
Cleft Palate Craniofac J
January 2025
Department of Otolaryngology - Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Objective: To determine whether palatoplasty technique affects the resolution of eustachian tube dysfunction and postoperative speech outcomes in children with cleft palate (CP).
Design: Retrospective cohort.
Setting: Multidisciplinary cleft and craniofacial clinic at a tertiary care center.
Laryngoscope Investig Otolaryngol
February 2025
Otorhinolaryngology and Head and Neck surgery Unidade Local de Saúde de Santo António Porto Portugal.
Background And Objective: Septoplasty and turbinate reduction surgery (STR) is hypothesized to affect pulmonary function by modifying airway dynamics. This study investigates the impact of STR-mediated improvements in nasal patency on pulmonary function tests (PFTs).
Methods: In a prospective analysis, 37 adult patients undergoing STR were enrolled.
Objectives: To evaluate the otolaryngology surgical capacity in Harare, Zimbabwe by analyzing procedural volumes across four hospitals, one private and three public, from 2019 to 2022.
Methods: A retrospective review of hand-written surgical case logs was conducted at Harare Eye, Ear, Nose, and Throat Institute (HEENT), Parirenyatwa Group of Hospitals (PGH), Sally Mugabe Children's Hospital (SMCH), and Sally Mugabe Adult's Hospital (SMAH). Patient age and surgical intervention for all otolaryngology surgeries performed in the operating room from 2019 to 2022 were recorded.
Korean J Radiol
January 2025
College of IT Engineering, Hansung University, Seoul, Republic of Korea.
Objective: To establish local diagnostic reference levels (DRLs) for pediatric neck CT based on age, weight, and water-equivalent diameter (WED) across multiple university hospitals in South Korea.
Materials And Methods: This retrospective study analyzed pediatric neck CT examinations from nine university hospitals, involving patients aged 0-18 years. Data were categorized by age, weight, and WED, and radiation dose metrics, including volume CT dose index (CTDI) and dose length product, were recorded.
Nat Commun
January 2025
Gleiberman Head and Neck Cancer Center, Moores Cancer Center, University of California San Diego Health, La Jolla, CA, 92037, USA.
Tumor initiation represents the first step in tumorigenesis during which normal progenitor cells undergo cell fate transition to cancer. Capturing this process as it occurs in vivo, however, remains elusive. Here we employ spatiotemporally controlled oncogene activation and tumor suppressor inhibition together with multiomics to unveil the processes underlying oral epithelial progenitor cell reprogramming into tumor initiating cells at single cell resolution.
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