Buschke-Lowenstein tumour.

BMJ Case Rep

Department of Dermatology, Venereology and Leprosy, BLDE Deemed to be University, Vijayapura, Karnataka, India

Published: January 2025

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Source
http://dx.doi.org/10.1136/bcr-2024-262618DOI Listing

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Buschke-Lowenstein tumour.

BMJ Case Rep

January 2025

Department of Dermatology, Venereology and Leprosy, BLDE Deemed to be University, Vijayapura, Karnataka, India

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The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.

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GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2.

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Article Synopsis
  • The Buschke-Löwenstein tumor (BLT) is a rare, exophytic tumor linked to low-risk HPV strains, primarily appearing as a large, cauliflower-like growth in genital areas, which can be locally aggressive and has a notable recurrence rate.
  • A 68-year-old patient with multiple health issues presented with a sizable tumor causing erectile dysfunction and urinary problems, which was successfully surgically excised with reconstruction.
  • Histopathological analysis confirmed the diagnosis, and the patient's recovery underscores the importance of early diagnosis and surgical intervention to manage BLT and prevent complications like malignancy and recurrence.
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