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The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001-2018.
BMC Cancer
January 2025
Department of family medicine & Division of General Internal Medicine, Department of internal medicine, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases (Peking Union Medical College Hospital), Chinese Academy of Medical Sciences, Beijing, China.
Background: Oxidative stress is a crucial pathophysiological mechanism in chronic diseases and mortality. While individual oxidative markers have been studied, the comprehensive impact of oxidative balance on mortality risks remains unclear, particularly among cancer survivors. We aimed to investigate the associations of Oxidative Balance Score (OBS) with mortality in both the general population and cancer survivors.
View Article and Find Full Text PDFLong-term Mental Health Morbidity in Adult Survivors of COVID-19 Critical Illness - A Population-based Cohort Study.
Chest
January 2025
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada; Institut du Savoir Montfort, Hôpital Montfort, Ottawa, ON, Canada.
Background: Survivorship after coronavirus disease 2019 (COVID-19) critical illness may be associated with important long-term sequelae, but little is known regarding mental health outcomes.
Research Question: What is the association between COVID-19 critical illness and new post-discharge mental health diagnoses.
Study Design: AND METHODS: We conducted a population-based cohort study in Ontario, Canada (January 1, 2020-March 31, 2022).
All-Cause and Cause-Specific Mortality in Children With Congenital Zika Syndrome in Brazil.
JAMA Netw Open
January 2025
Center of Data and Knowledge Integration for Health, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil.
Importance: Congenital Zika syndrome (CZS) can lead to a range of developmental and neurological issues, which increases the risk of early death. However, the all-cause and cause-specific mortality in children with CZS in the first 5 years of life remain unknown.
Objective: To compare the hazard of all-cause and cause-specific mortality before age 5 years among children with and without CZS in Brazil.
Joint Physical-Psychosocial Frailty and Risks of All-Cause and Cause-Specific Premature Mortality.
J Gen Intern Med
January 2025
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 1724, New Orleans, LA, 70112, USA.
Background: The importance of integrating physical and psychosocial factors in assessing frailty -health outcomes has been increasingly acknowledged, while the related evidence is lacking. We sought to investigate the associations of joint physical-psychosocial frailty with risk of premature mortality and evaluate the relative importance of individual physical and psychosocial factors.
Design: A total of 381,295 participants with no history of cancer or cardiovascular disease (CVD) were recruited from the UK Biobank cohort.
Rurality and neighborhood socioeconomic status are associated with overall and cause-specific mortality and hepatic decompensation in type 2 diabetes.
Am J Med
January 2025
Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Veterans Affairs Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA; Gastroenterology Section, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
Introduction: Social determinants of health are key factors driving disease progression. In type 2 diabetes there is limited literature on how distal or intermediate factors (e.g.
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