The split torque gear transmission holds significant potential for use in helicopter main reducer transmission systems due to its benefits of low noise, high power-to-weight ratio, and high reliability. In this context, a nonlinear dynamic equation was formulated in the present study for a single-input dual-output gear split-torque transmission system, and the system's dynamic behavior was examined under the effects of center distance error and backlash using the fourth-order Runge-Kutta method. The findings indicate that the impact of center distance error on the system's dynamics is linear, whereas the effect of backlash is nonlinear. Moreover, the center distance error in the parallel-level stage and the backlash in the split-torsion stage are critical factors influencing the system's dynamic characteristics. These insights can aid in selecting and allocating design parameters, offering valuable practical applications in engineering.
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http://dx.doi.org/10.1038/s41598-024-81753-9 | DOI Listing |
Alzheimers Dement
December 2024
Department of Biomedical Engineering, McGill University, Montreal, QC, Canada.
Background: Randomized placebo-controlled trials (RCTs) are the gold standard to evaluate efficacy of new drug treatments for Alzheimer's disease. For example, the United States FDA approved the brain amyloid-targeting drug lecanemab following CLARITY AD, Biogen and Eisai's Phase 3 RCT. However, recruiting enough participants for a high-powered and demographically representative trial is difficult and expensive.
View Article and Find Full Text PDFHistol Histopathol
December 2024
Laboratory of Anatomy, Department of Basic Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Sex hormones regulate gut function and mucosal immunity; however, their specific effects on the mucosa-associated lymphoid tissue (MALT) in the rectum of mammals remain unclear. Here, we aimed to investigate the influence of sex on MALT in the rectum of mammals by focusing on the rectal mucosa-associated lymphoid tissues (RMALTs) of C57BL/6NCrSIc mice. Histological analysis revealed that RMALTs were predominantly located in the lamina propria and submucosa of the rectal mucosa, with a significant sex-related difference in the distance from the anorectal junction to the first appearance of the RMALT.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
German Center for Neurodegenerative Diseases e.V. (DZNE), Site Rostock/Greifswald, Greifswald, Germany.
Background: Proxy ratings primarily provided by informal caregivers are usually administered if patients living with dementia (PlwD) are cognitively unable to rate health independently. The literature is limited by the use of typically agreement statistics, reporting that proxies generally underestimate PlwD health. Additional analyses of self- and proxy-rated discrepancies in individual responses that focus on HRQoL dimensions are lacking.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
National Institute of Mental Health and Neurosciences [NIMHANS], Bengaluru, Karnataka, India.
Background And Objectives: Telemedicine, including teleneurology, has emerged as a valuable tool for providing healthcare services remotely, particularly in situations where distance plays a critical role. Teleneurology has the potential to increase access to care, improve patient outcomes, and reduce healthcare costs, especially for patients in rural and underserved areas. We aimed to investigate patients and health care providers satisfaction with teleneurology for dementia.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
National Institute of Mental Health and Neurosciences [NIMHANS], Bengaluru, Karnataka, India.
Background And Objectives: Telemedicine, including teleneurology, has emerged as a valuable tool for providing healthcare services remotely, particularly in situations where distance plays a critical role. Teleneurology has the potential to increase access to care, improve patient outcomes, and reduce healthcare costs, especially for patients in rural and underserved areas. We aimed to investigate patients and health care providers satisfaction with teleneurology for dementia.
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