Lupus Nephritis Revealed by FAPI PET/CT.

Clin Nucl Med

From the Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Published: November 2024

A 38-year-old woman received a 68Ga-FAPI-04 PET/CT scan for the evaluation of systemic lupus erythematosus. Diffuse uptake in both kidney parenchyma indicated the presence of lupus nephritis. In addition, an incidental carotid body tumor with increased FAPI uptake was also observed. Our case described the imaging features of lupus nephritis coexistent with a carotid body tumor on FAPI PET/CT.

Download full-text PDF

Source
http://dx.doi.org/10.1097/RLU.0000000000005598DOI Listing

Publication Analysis

Top Keywords

lupus nephritis
12
fapi pet/ct
8
carotid body
8
body tumor
8
lupus
4
nephritis revealed
4
revealed fapi
4
pet/ct 38-year-old
4
38-year-old woman
4
woman received
4

Similar Publications

Immunoglobulin G4-related disease (IgG4-RD) and systemic lupus erythematosus (SLE) are multisystemic autoimmune disorders that can present with renal manifestations. Overlapping cases of these diseases are extremely rare and present both diagnostic and therapeutic challenges. We report the case of a 70-year-old male with a history of autoimmune pancreatitis, who was admitted with fatigue, weight loss, and worsening kidney function.

View Article and Find Full Text PDF

When systematic lupus erythematosus-like lab results (e.g., positive anti-double-stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses such as Wilson's disease, especially in the presence of abnormal liver function and elevated international normalized ratio (INR).

View Article and Find Full Text PDF

IgA nephropathy (IgAN) is one of the most common primary glomerular diseases worldwide and is the most common cause of chronic kidney disease (CKD) in China. It lacks recommended treatment in refractory IgAN after conventional therapy. Belimumab, a recombinant human IgG-1λ monoclonal antibody that inhibits the B lymphocyte stimulator, is recommended to treat active lupus nephritis.

View Article and Find Full Text PDF

Lupus Nephritis and Chronic Kidney Disease: A Scoping Review.

Nephrology (Carlton)

January 2025

Division of Nephrology, School of Clinical Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong SAR.

Prevention of end-stage kidney disease (ESKD) is a major objective in the management of patients with lupus nephritis (LN). Chronic kidney disease (CKD) of variable severity is common in these patients, but recent literature has mostly focused on novel immunosuppressive treatments for acute LN, while the data on CKD is relatively limited. This scoping review aims to summarise available data on the prevalence and risk factors for CKD in patients with LN.

View Article and Find Full Text PDF

Lupus Nephritis Revealed by FAPI PET/CT.

Clin Nucl Med

November 2024

From the Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

A 38-year-old woman received a 68Ga-FAPI-04 PET/CT scan for the evaluation of systemic lupus erythematosus. Diffuse uptake in both kidney parenchyma indicated the presence of lupus nephritis. In addition, an incidental carotid body tumor with increased FAPI uptake was also observed.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!