Quorum quenching nanoparticles against wound pathogens - A scoping review.

Introduction: Quorum sensing (QS) enables bacteria to coordinate colony-wide activities, including those associated with infections. Quorum quenching (QQ) inhibits QS and is a promising method for controlling bacterial infections. Several In vitro experiments have been conducted to identify nanoparticles (NPs) as potential quorum quenching inhibitors. This review examines the potential of nanoparticles for quorum quenching, focusing on the QS-regulated pathogenicity of wound pathogens.

Materials And Methods: Observational studies were conducted to explore the capacity of nanoparticles to quorum quench wound pathogens.

Results: A review of observational studies indicated that nanoparticles exhibit significant quorum-quenching capabilities against wound pathogens. Numerous nanoparticles, including silver, gold, and zinc oxide, have been demonstrated to inhibit QS-regulated activities, thereby reducing bacterial virulence and biofilm formation. These results suggest that nanoparticles could serve as potent agents for mitigating bacterial infections and enhancing wound healing.

Conclusion: Nanoparticles show considerable potential as quorum-quenching agents, effectively decreasing bacterial virulence and biofilm formation in wound pathogens. These results indicate promising applications of nanoparticles in managing bacterial infections and improving wound healing.