Climate change caused by greenhouse gas (GHG) emissions is an escalating global issue, with the transportation sector being a significant contributor, accounting for approximately a quarter of all energy-related GHG emissions. In the transportation sector, vehicle emissions testing is a key part of ensuring compliance with environmental regulations. The Vehicle Certification Agency (VCA) of the UK plays a pivotal role in certifying vehicles for compliance with emissions and safety standards. One of the primary methods employed by the VCA to measure vehicle emissions for light-duty vehicles is the Worldwide Harmonized Light Vehicles Test Procedure (WLTP). The WLTP is a global standard for testing vehicle emissions and fuel consumption, and sensors are crucial in ensuring accurate, real-time data collection in laboratories. Using the data collected by the VCA, regression machine learning models were trained to predict CO emissions in light-duty vehicles. Among six regression models tested, the Decision Tree Regression model achieved the highest accuracy, with a Mean Absolute Error (MAE) of 2.20 and a Mean Absolute Percentage Error (MAPE) of 1.69%. It was then deployed as a web application that provides users with accurate CO emission estimates for vehicles, enabling informed decisions to reduce GHG emissions. This research demonstrates the efficacy of machine learning and AI-driven approaches in fostering sustainability within the transportation sector.
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http://dx.doi.org/10.3390/s24248219 | DOI Listing |
Exp Ther Med
February 2025
Department of Emergency, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, Hubei 437199, P.R. China.
Previous research has highlighted the critical role of amino acid metabolism (AAM) in the pathophysiology of sepsis. The present study aimed to explore the potential diagnostic and prognostic value of AAM-related genes (AAMGs) in sepsis, as well as their underlying molecular mechanisms. Gene expression profiles from the Gene Expression Omnibus (GSE65682, GSE185263 and GSE154918 datasets) were analyzed.
View Article and Find Full Text PDFPatterns (N Y)
December 2024
Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO, USA.
Guidelines in statistical modeling for genomics hold that simpler models have advantages over more complex ones. Potential advantages include cost, interpretability, and improved generalization across datasets or biological contexts. We directly tested the assumption that small gene signatures generalize better by examining the generalization of mutation status prediction models across datasets (from cell lines to human tumors and vice versa) and biological contexts (holding out entire cancer types from pan-cancer data).
View Article and Find Full Text PDFFront Chem
December 2024
African Society for Bioinformatics and Computational Biology, Cape Town, South Africa.
Introduction: Dengue Fever continues to pose a global threat due to the widespread distribution of its vector mosquitoes, and . While the WHO-approved vaccine, Dengvaxia, and antiviral treatments like Balapiravir and Celgosivir are available, challenges such as drug resistance, reduced efficacy, and high treatment costs persist. This study aims to identify novel potential inhibitors of the Dengue virus (DENV) using an integrative drug discovery approach encompassing machine learning and molecular docking techniques.
View Article and Find Full Text PDFObjective: To investigate machine learning-based regression models to predict the postoperative apnea-hypopnea index (AHI) for evaluating the outcome of velopharyngeal surgery in adult obstructive sleep apnea (OSA) subjects.
Study Design: A single-center, retrospective, cohort study.
Setting: Sleep medical center.
Objective: To analyze the accuracy of ChatGPT-generated responses to common rhinologic patient questions.
Methods: Ten common questions from rhinology patients were compiled by a panel of 4 rhinology fellowship-trained surgeons based on clinical patient experience. This panel (Panel 1) developed consensus "expert" responses to each question.
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