One of the most promising applications for electroencephalogram (EEG)-based brain-computer interfaces (BCIs) is motor rehabilitation through motor imagery (MI) tasks. However, current MI training requires physical attendance, while remote MI training can be applied anywhere, facilitating flexible rehabilitation. Providing remote MI training raises challenges to ensuring an accurate recognition of MI tasks by healthcare providers, in addition to managing computation and communication costs. The MI tasks are recognized through EEG signal processing and classification, which can drain sensor energy due to the complexity of the data and the presence of redundant information, often influenced by subject-dependent factors. To address these challenges, we propose in this paper a multi-subject transfer-learning approach for an efficient MI training framework in remote rehabilitation within an IoT environment. For efficient implementation, we propose an IoT architecture that includes cloud/edge computing as a solution to enhance the system's efficiency and reduce the use of network resources. Furthermore, deep-learning classification with and without channel selection is applied in the cloud, while multi-subject transfer-learning classification is utilized at the edge node. Various transfer-learning strategies, including different epochs, freezing layers, and data divisions, were employed to improve accuracy and efficiency. To validate this framework, we used the BCI IV 2a dataset, focusing on subjects 7, 8, and 9 as targets. The results demonstrated that our approach significantly enhanced the average accuracy in both multi-subject and single-subject transfer-learning classification. In three-subject transfer-learning classification, the FCNNA model achieved up to 79.77% accuracy without channel selection and 76.90% with channel selection. For two-subject and single-subject transfer learning, the application of transfer learning improved the average accuracy by up to 6.55% and 12.19%, respectively, compared to classification without transfer learning. This framework offers a promising solution for remote MI rehabilitation, providing both accurate task recognition and efficient resource usage.
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Front Sports Act Living
December 2024
School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.
It is essential in combat sports such as boxing for athletes to perceive the relevant visual information that enables them to anticipate and respond to their opponent's attacking and defensive moves. Here, we used virtual reality (VR), which enables standardization and reproducibility while maintaining perception-action coupling, to assess the influence of a gaze-contingent blur on the visual processes that underpin these boxing behaviours. Eleven elite French boxers were placed in an immersive and adaptive first-person VR environment where they had to avoid by dodging one or two punches, and then counterattack to strike their opponent.
View Article and Find Full Text PDFExp Ther Med
February 2025
Department of Emergency, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, Hubei 437199, P.R. China.
Previous research has highlighted the critical role of amino acid metabolism (AAM) in the pathophysiology of sepsis. The present study aimed to explore the potential diagnostic and prognostic value of AAM-related genes (AAMGs) in sepsis, as well as their underlying molecular mechanisms. Gene expression profiles from the Gene Expression Omnibus (GSE65682, GSE185263 and GSE154918 datasets) were analyzed.
View Article and Find Full Text PDFPatterns (N Y)
December 2024
Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO, USA.
Guidelines in statistical modeling for genomics hold that simpler models have advantages over more complex ones. Potential advantages include cost, interpretability, and improved generalization across datasets or biological contexts. We directly tested the assumption that small gene signatures generalize better by examining the generalization of mutation status prediction models across datasets (from cell lines to human tumors and vice versa) and biological contexts (holding out entire cancer types from pan-cancer data).
View Article and Find Full Text PDFFront Chem
December 2024
African Society for Bioinformatics and Computational Biology, Cape Town, South Africa.
Introduction: Dengue Fever continues to pose a global threat due to the widespread distribution of its vector mosquitoes, and . While the WHO-approved vaccine, Dengvaxia, and antiviral treatments like Balapiravir and Celgosivir are available, challenges such as drug resistance, reduced efficacy, and high treatment costs persist. This study aims to identify novel potential inhibitors of the Dengue virus (DENV) using an integrative drug discovery approach encompassing machine learning and molecular docking techniques.
View Article and Find Full Text PDFObjective: To investigate machine learning-based regression models to predict the postoperative apnea-hypopnea index (AHI) for evaluating the outcome of velopharyngeal surgery in adult obstructive sleep apnea (OSA) subjects.
Study Design: A single-center, retrospective, cohort study.
Setting: Sleep medical center.
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