Identifying breast masses is relevant in early cancer detection. Automatic identification using computational methods helps assist medical experts with this task. Although high values have been reported in breast mass classification from digital mammograms, most results have focused on a general benign/malignant classification. According to the BI-RADS standard, masses are associated with cancer risk by grade depending on their specific shape, margin, and density characteristics. This work presents a methodology of testing several descriptors on the INbreast dataset, finding those better related to clinical assessment. The analysis provides a description based on BI-RADS for mass classification by combining neural networks and image processing. The results show that masses associated with grades BI-RADS-2 to BI-RADS-5 can be identified, reaching a general accuracy and sensitivity of 0.88±0.07. While this initial study is limited to a single dataset, it demonstrates the possibility of generating a description for automatic classification that is directly linked to the information analyzed by medical experts in clinical practice.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11677739 | PMC |
http://dx.doi.org/10.3390/life14121634 | DOI Listing |
Objective: To clarify the screening behavior and influencing factors of females with breast cancer and cervical cancer in suburban areas and to provide a scientific basis for the subsequent implementation of targeted health education, intervention measures and the formulation of relevant policies.
Methods: This study used a multi-stage stratified random sampling method to select 4, 000 women in urban and rural areas of Beijing to analyze their behavior, basic situation, and influencing factors regarding cervical and breast cancer screening.
Results: The sample size of the final included valid analysis was 3861 people, and the screening rate was 27.
Am J Physiol Cell Physiol
January 2025
Interdisciplinary Department of Medicine, University of Bari Aldo Moro School of Medicine, Piazza G. Cesare, 11 - 70124 Bari, Italy.
Resistance to drugs is one of the major issues affecting the response to pharmacological treatments for tumors. Different mechanisms have been proposed to explain the development of cancer drug resistance (CDR), and several approaches to overcome it have been suggested. However, the biological basis of CDR remains unclear.
View Article and Find Full Text PDFCurr Issues Mol Biol
January 2025
The M-Lab, Department of Precision Medicine, GROW-Research Institute for Oncology and Reproduction, Maastricht University, 6200MD Maastricht, The Netherlands.
Background/aim: Flavonoids are a group of polyphenols, abundantly present in our diet. Although, based on their chemoprotective effects, intake of flavonoids is associated with a high anticancer potential as evidenced in in vitro and in vivo models, the molecular mechanism is still elusive. This study explores the antiproliferative and cytotoxic effects of the semi-synthetic flavonoid MonoHER (7-mono-O-(β-hydroxyethyl)-rutoside) in vitro on cancer cells.
View Article and Find Full Text PDFPol J Pathol
January 2025
Department of Breast Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology and Hubei Provincial Clinical Research Center for Breast Cancer, Wuhan, Hubei, P. R. China.
Low-grade myofibroblastic sarcoma is an uncommon malignancy that can be difficult to identify and for which there is no unified treatment protocol. We report herein a case of an 81-year-old male who presented with a giant irregular breast mass and was diagnosed with low-grade myofibroblastic sarcoma. In this study we summarise the clinicopathological features of 13 reported cases of myofibroblastic sarcoma arising in the breast, present the diagnostic process and treatment procedure of our case, and discuss the differential diagnosis from other similar diseases, to provide constructive information and promote deep understanding of myofibroblastic sarcoma in the future.
View Article and Find Full Text PDFBiomark Res
January 2025
Laboratory of Cellular Therapy, Department of Medical and Surgical Sciences for Children and Adults, University Hospital of Modena, Modena, 41124, Italy.
Emerging evidence highlights the key role of microRNA (miR)-21 in cell-to-cell communication and tumorigenesis. However, limited knowledge exists on the levels and clinical meaning of miR-21 in extracellular vesicles (EVs) of patients with breast cancer (BC). We assessed EV-derived miR-21 levels in one hundred women: 30 with early BC (EBC), 30 with metastatic BC on treatment progression (MBC), 30 cancer survivors on follow-up (FU) and 10 healthy donors (HD) as age- and body mass index (BMI)-matched controls.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!