The implementation of clinical 7T MRI presents both opportunities and challenges for advanced medical imaging. This tutorial provides practical considerations and experiences with 7T MRI in clinical settings. We first explore the history and evolution of MRI technology, highlighting the benefits of increased signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and susceptibility at 7T. Technical challenges such as increased susceptibility artifacts and RF inhomogeneity are also discussed, along with innovative adaptations. This review also discusses hardware and software considerations, including new parallel transmission head coils and advanced image processing techniques to optimize image quality. Safety considerations, such as managing tissue heating and susceptibility to artifacts, are also discussed. Additionally, clinical applications of 7T MRI are examined, focusing on neurological conditions such as epilepsy, multiple sclerosis, and vascular imaging. Emerging trends in the use of 7T MRI for spectroscopy, perfusion imaging, and multinuclear imaging are explored, with insights into the future of ultra-high-field MRI in clinical practice. This review aims to provide clinicians, technologists, and researchers with a roadmap for successfully implementing 7T MRI in both research and clinical environments.
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http://dx.doi.org/10.3390/bioengineering11121228 | DOI Listing |
Int J Cardiovasc Imaging
January 2025
Department of Clinical Radiology, AHEPA University Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece.
The term acute aortic syndrome (AAS) refers to a range of different entities, including dissection, intramural haematoma and penetrating atherosclerotic ulcer. Patients with chronic renal disease and particularly those with dominant polycystic kidney disease are susceptible to this pathology, given the underlying renal arteriopathy and hypertension. Imaging plays a crucial role in diagnosing, grading and guiding management of these patients, with computed tomography angiography (CTA) being on the frontline.
View Article and Find Full Text PDFInferior frontal sulcal hyperintensities (IFSH) observed on fluid-attenuated inversion recovery (FLAIR) MRI have been proposed as indicators of elevated cerebrospinal fluid waste accumulation in cerebral small vessel disease (CSVD). However, to validate IFSH as a reliable imaging biomarker, further replication studies are required. The objective of this study was to investigate associations between IFSH and CSVD, and their potential repercussions, i.
View Article and Find Full Text PDFHypertens Res
January 2025
Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA.
The brainstem plays a vital role in regulating blood pressure, and disruptions to its neural pathways have been linked to hypertension. However, it remains unclear whether subtle microstructural changes in the brainstem are associated with an individual's blood pressure status. This exploratory, cross-sectional study investigated the relationship between brainstem microstructure, myelination, and hypertensive status in 116 cognitively unimpaired adults (aged 22-94 years).
View Article and Find Full Text PDFJ Neurol
January 2025
Department of Neurology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL, 60637, USA.
Positional downbeat nystagmus (pDBN) is a common finding in dizzy patients, with etiologies ranging from benign paroxysmal positional vertigo (BPPV) to central vestibular lesions. Although peripheral pDBN often presents with distinct clinical features that differentiate it from BPPV, diagnosing its etiology can be challenging. A thorough clinical evaluation, including the physical characteristics of the nystagmus, response to positional maneuvers, and neurological findings, is often sufficient to diagnose conditions that provoke pDBN such as anterior canal BPPV, atypical posterior canal BPPV, and central causes.
View Article and Find Full Text PDFZhongguo Gu Shang
January 2025
Department of Orthopaedics, Sir Run Run Shaw Hospital, Hangzhou 310016, Zhejiang, China.
Objective: To observe the clinical outcomes of anterior approach for the revision surgery following unsuccessful bone cement augmentation in osteoporotic vertebral compression fractures.
Methods: A total of 10 patients who experienced unsuccessful bone cement augmentation underwent anterior revision surgery between January 2020 and December 2021. There were 2 males and 8 females.
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