Background/objectives: Children with autism exhibit deficits in fundamental motor skills, which are intensified when associated with attention-deficit/hyperactivity disorder (ADHD).
Objective: To correlate motor competence in children with autism, autism levels according to the CARS scale, and the association with ADHD.
Methods: This cross-sectional study assessed motor competence using the Motor Competence Assessment (MCA), the severity of Autism Spectrum Disorder by Childhood Autism Rating Scale (CARS), and the presence of clinical signs for ADHD using Swanson, Nolan, and Pelham (SNAP-IV) questionnaire. A total of 68 children were recruited; however, 23 were not included due to non-acceptance and/or were excluded because of associated pathologies, high autism severity. Consequently, 45 children (11 with ADHD) between the ages of 5 and 11 (Mean: 8.15; ±1.75) with 83.72% being male.
Results: Multiple linear regression revealed a significant inverse correlation between MCA scores and raw CARS data ( = 0.01), indicating that greater autism severity is associated with lower motor competence. The correlation was also observed in CARS classifications, with higher autism severity corresponding to lower motor percentiles ( = 0.05). However, the correlation between the presence of ADHD and motor competence in children with ASD did not reach significance. Overall, a significant correlation was observed ( = 0.006) when analyzing all variables (CARS scores, SNAP scores, and CARS classification).
Conclusion: Therefore, it is believed that children with autism exhibit deficits in functional motor skills, with severity impacting motor competence. The findings underscore the need for systematic motor skill assessments in children with autism, emphasizing the importance of monitoring and intervention in this aspect of their development.
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http://dx.doi.org/10.3390/children11121518 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Marmara University, İstanbul, Turkey.
Background: No other study has addressed the effectiveness of dual-task training in the postoperative period of total hip arthroplasty (THA). This study investigated the efficacy of dual-task training in older adults with THA.
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Evid Based Dent
January 2025
Department of Public Health Dentistry, Coorg Institute of Dental Sciences, Virajpet, Karnataka, 571218, India.
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The Hybrid-Brain Computer Interface (BCI) has shown improved performance, especially in classifying multi-class data. Two non-invasive BCI modules are combined to achieve an improved classification which are Electroencephalogram (EEG) and functional Near Infra-red Spectroscopy (fNIRS). Classifying contralateral and ipsilateral motor movements is found challenging among the other mental activity signals.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Biomedical Engineering, Faculty of Mechanical and Electrical Engineering, Damascus University, Damascus 86, Syria.
Gait analysis is crucial for identifying functional deviations from the normal gait cycle and is essential for the individualized treatment of motor disorders such as cerebral palsy (CP). The primary contribution of this study is the introduction of a multimodal fuzzy logic system-based gait index (FLS-GIS), designed to provide numerical scores for gait patterns in both healthy children and those with CP, before and after surgery. This study examines and evaluates the surgical outcomes in children with CP who have undergone Achilles tendon lengthening.
View Article and Find Full Text PDFNPJ Parkinsons Dis
January 2025
Department of Neurobiology, Center of Parkinson Disease Beijing Institute for Brain Disorders, Beijing Key Laboratory on Parkinson Disease, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory of Neural Regeneration and Repair, Capital Medical University, Beijing, 100069, China.
Chronic neuroinflammation with sustained microglial activation occurs in Parkinson's disease (PD), yet the mechanisms and exact contribution of these cells to the neurodegeneration remains poorly understood. In this study, we induced progressive dopaminergic neuron loss in mice via rAAV-hSYN injection to cause the neuronal expression of α-synuclein, which produced neuroinflammation and behavioral alterations. We administered PLX5622, a colony-stimulating factor 1 receptor inhibitor, for 3 weeks prior to rAAV-hSYN injection, maintaining it for 8 weeks to eliminate microglia.
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