Unlabelled: Background and Clinical Significance: Sarcopenia, characterized by muscle loss and fat infiltration, poses a significant health burden for aging populations. Quantitative Color 2D and 3D radiodensitometry provides a powerful tool to monitor muscle quality and quantity through CT imaging. This study assessed the impact of a ten-year-long home-bed gym exercise intervention on muscle quality in an elderly subject using CT-derived radiodensitometric analysis. The study involved two comparative analyses: Study A, which compared knee-to-ankle CT scans of the subject between 2013 and 2023; and Study B, which compared the subject's 2023 thigh CT scan with a cohort of 2500 elderly Icelandic individuals from the AGES-Reykjavik study.
Case Presentation: A 70-year-old male began a home-based Full-Body In-Bed Gym exercise program in 2013. Quantitative muscle volume and radiodensity measurements were performed using CT at baseline and after ten years.
Results: Study A shows significant improvements in muscle volume observed in the knee-to-ankle region, while a slower decline in radiodensity was noted, indicating substantial preservation of muscle quality despite the expected decay of ten-year aging. For instance, muscle volume increased by 15% in the left Soleus muscle and by 6% in the right Soleus muscle, while the average radiodensity decreased by 12-17 HU. The subject's thigh muscle quality at 80-years-old is above the AGES-Reykjavik's cohort average, with reduced fat infiltration.
Conclusions: Long-term home Full-Body In-Bed Gym, a low-impact exercise, can mitigate aging sarcopenia, as evidenced by improved tissue radiodensity and muscle mass substantial preservation. This suggests potential applications in personalized healthcare strategies to enhance muscle preservation among aging populations.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11674620 | PMC |
http://dx.doi.org/10.3390/diagnostics14242808 | DOI Listing |
Eur Urol
January 2025
Department of Urology, Freeman Hospital Newcastle-upon-Tyne UK; Translational and Clinical Research Institute, Newcastle University Newcastle-upon-Tyne UK.
Background And Objective: Stress urinary incontinence (SUI), defined as any involuntary leakage of urine associated with physical activity, remains underdiagnosed and undertreated. This review aims to provide an updated overview of the prevalence, diagnosis, and treatment of SUI in women, drawing upon recent evidence-based literature and clinical guidelines.
Methods: A systematic search of the MEDLINE database was conducted to identify only the most up-to-date and relevant studies published up to February 26, 2024, including the reference ESTER systematic review.
Mol Cell Endocrinol
January 2025
Department of Physiology and Biophysics, Rush University, Chicago, United States.
The incidence and prevalence of muscular disorders and of type 2 diabetes (T2D) is increasing and both represent highly significant healthcare problems, both economically and compromising quality of life. Interestingly, skeletal muscle dysfunction and T2D share some commonalities including dysregulated glucose homeostasis, increased oxidative stress, dyslipidemia, and cytokine alterations. Several lines of evidence have hinted to a relationship between skeletal muscle dysfunction and T2D.
View Article and Find Full Text PDFJ Arthroplasty
January 2025
Anshin Hospital, Kobe, Japan.
Background: Total hip arthroplasty (THA) effectively enhances hip function and alleviates pain in patients who have osteoarthritis, improving their quality of life. The Forgotten Joint Score-12 (FJS-12), a patient-reported outcome measure, has recently gained attention as a method for assessing joint awareness during daily activities following THA; however, the association between muscle strength, specifically quadriceps muscle strength, and the FJS-12 has not been fully investigated.
Methods: This cross-sectional study involved 624 patients who underwent THA at a single center in Japan.
Poult Sci
January 2025
Department of Biology and Animal Environment, Bydgoszcz University of Science and Technology, 85-084 Bydgoszcz, Poland.
This research aimed to determine the effect of intramuscular fat (IMF) levels in m. pectoralis major on carcass weight and composition, meat of male broiler chickens. Whole eviscerated necked carcasses of Ross 308 male broiler chickens aged 42 days were purchased from a commercial poultry slaughterhouse.
View Article and Find Full Text PDFEur J Radiol
January 2025
Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. Electronic address:
Purpose: To quantitatively verify whether degeneration in the quality of the medial femoral cartilage is correlated with muscle volume loss and intramuscular adipose tissue (IntraMAT) infiltration in quadriceps using magnetic resonance imaging (MRI).
Methods: Of the 66 older adult participants ≥60 years old (74.5 ± 6.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!