Image segmentation is a crucial task in artificial intelligence fields such as computer vision and medical imaging. While convolutional neural networks (CNNs) have achieved notable success by learning representative features from large datasets, they often lack geometric priors and global object information, limiting their accuracy in complex scenarios. Variational methods like active contours provide geometric priors and theoretical interpretability but require manual initialization and are sensitive to hyper-parameters. To overcome these challenges, we propose a novel segmentation approach, named PolarVoting, which combines the minimal path encoding rich geometric features and CNNs which can provide efficient initialization. The introduced model involves two main steps: firstly, we leverage the PolarMask model to extract multiple source points for initialization, and secondly, we construct a voting score map which implicitly contains the segmentation mask via a modified circular geometric voting (CGV) scheme. This map embeds global geometric information for finding accurate segmentation. By integrating neural network representation with geometric priors, the PolarVoting model enhances segmentation accuracy and robustness. Extensive experiments on various datasets demonstrate that the proposed PolarVoting method outperforms both PolarMask and traditional single-source CGV models. It excels in challenging imaging scenarios characterized by intensity inhomogeneity, noise, and complex backgrounds, accurately delineating object boundaries and advancing the state of image segmentation.
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http://dx.doi.org/10.3390/e26121123 | DOI Listing |
BMC Med Inform Decis Mak
January 2025
Department of Digital Systems, University of Piraeus, Piraeus, Greece.
Vitiligo, alopecia areata, atopic, and stasis dermatitis are common skin conditions that pose diagnostic and assessment challenges. Skin image analysis is a promising noninvasive approach for objective and automated detection as well as quantitative assessment of skin diseases. This review provides a systematic literature search regarding the analysis of computer vision techniques applied to these benign skin conditions, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
View Article and Find Full Text PDFBMC Infect Dis
January 2025
Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC, Australia.
Background: Early diagnosis of syphilis is vital for its effective control. This study aimed to develop an Artificial Intelligence (AI) diagnostic model based on radiomics technology to distinguish early syphilis from other clinical skin lesions.
Methods: The study collected 260 images of skin lesions caused by various skin infections, including 115 syphilis and 145 other infection types.
Sci Rep
January 2025
Divisions of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN, 55455, USA.
OrthoFusion, an intuitive super-resolution algorithm, is presented in this study to enhance the spatial resolution of clinical CT volumes. The efficacy of OrthoFusion is evaluated, relative to high-resolution CT volumes (ground truth), by assessing image volume and derived bone morphological similarity, as well as its performance in specific applications in 2D-3D registration tasks. Results demonstrate that OrthoFusion significantly reduced segmentation time, while improving structural similarity of bone images and relative accuracy of derived bone model geometries.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Computer Science and Information Technology, Benazir Bhutto Shaheed University Lyari, Karachi, 75660, Pakistan.
Deep learning-based medical image analysis has shown strong potential in disease categorization, segmentation, detection, and even prediction. However, in high-stakes and complex domains like healthcare, the opaque nature of these models makes it challenging to trust predictions, particularly in uncertain cases. This sort of uncertainty can be crucial in medical image analysis; diabetic retinopathy is an example where even slight errors without an indication of confidence can have adverse impacts.
View Article and Find Full Text PDFPharm Res
January 2025
Synthetic Molecule Pharmaceutical Sciences, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Purpose: The purpose of this study is to present a correlative microscopy-tomography approach in conjunction with machine learning-based image segmentation techniques, with the goal of enabling quantitative structural and compositional elucidation of real-world pharmaceutical tablets.
Methods: Specifically, the approach involves three sequential steps: 1) user-oriented tablet constituent identification and characterization using correlative mosaic field-of-view SEM and energy dispersive X-ray spectroscopy techniques, 2) phase contrast synchrotron X-ray micro-computed tomography (SyncCT) characterization of a large, representative volume of the tablet, and 3) constituent segmentation and quantification of the imaging data through user-guided, iterative supervised machine learning and deep learning.
Results: This approach was implemented on a real-world tablet containing 15% API and multiple common excipients.
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