Antecedents: Executive functions (EFs) are the basis for establishing a goal and working towards that goal by coordinating thoughts and actions. EFs are fundamental to several aspects of daily life, specifically for academic performance.
Aim: To analyse and compare the development of EFs in the transition period between the first and second cycles of early childhood education.
Methodology: Non-experimental methodology, ex post facto design, descriptive, cross-sectional evolution study.
Participants: Preschoolers of different educational levels (first and second cycle of infant education). In this study, the participants were evaluated by different informants: 54.42% by parents and 45.58% by teachers. In relation to gender, 52.65% were male and 47.35% were female. In relation to age, 37.54% had a range of 2-3 years and 62.46% had a range of 4-5 years.
Measurement: The instrumental development of EFs was evaluated using BRIEF-P by key informants.
Results: Preschoolers in the first cycle showed significantly higher scores than preschoolers in the second cycle in BRIEP-P.
Conclusions: The development of EFs is key in these first key moments, having a special impact on later development and academic performance. It is necessary to work on EFs from the first cycle of early childhood education, considering the evolutionary development of EFs.
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http://dx.doi.org/10.3390/brainsci14121273 | DOI Listing |
BMC Geriatr
January 2025
Division of Geriatrics, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Topkapi, Turgut Ozal Millet Street, Fatih/Istanbul, 34093, Türkiye.
Objective: The Simpler Modified Fried Frailty Scale (SMFFS) has recently been developed from the original Fried scale to ease its use in clinical practice, by transforming the items requiring measurements into the self-reported inquiries. Its predictive validity needs to be clarified, especially in populations with a high prevalence of frailty, such as patients with heart failure (HF). Primary aim of this study is to find out the prevalence of frailty in older patients with HF by using SMFFS and show its concordance with other frailty assessment tools.
View Article and Find Full Text PDFJ Child Adolesc Ment Health
January 2025
Department of Occupational Therapy, University of Haifa, Haifa, Israel.
Eating Disorders (ED) are prevalent in female adolescents and have far-reaching effects on daily participation and quality of life (QoL). Daily participation highly depends on Executive Functions (EF). Existing knowledge about EF in ED, as expressed in real life, is not fully documented or clear.
View Article and Find Full Text PDFNeurol Educ
December 2024
From the Department of Neurology Feinberg School of Medicine (S.V.), Northwestern University, Chicago, IL; Baylor College of Medicine (D.K.), Houston, TX; University of Texas Health Science Center at Houston (E.F.S.), McGovern Medical School; Mayo Clinic (J.K.C.-G.), Rochester, MN; Weill Cornell Medical College (J.W.), New York, NY; American Academy of Neurology (C.M.C., T.O., C.M.K.), Minneapolis, MN.
Background And Objectives: To report a 2022 survey of US medical school neurology clerkship directors (CDs) and to compare the results with those of similar surveys conducted in 2005, 2012, and 2017.
Methods: An American Academy of Neurology (AAN) Consortium of Neurology Clerkship Directors (CNCD) workgroup developed the survey sent to all neurology CDs listed in the AAN CNCD database. Comparisons were made with 2005, 2012, and 2017 surveys.
Hemasphere
January 2025
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, UNSW Centre for Childhood Cancer Research UNSW Sydney Sydney New South Wales Australia.
Antibody-drug conjugates (ADCs) combining monoclonal antibodies with cytotoxic payloads are a rapidly emerging class of immune-based therapeutics with the potential to improve the treatment of cancer, including children with relapse/refractory acute lymphoblastic leukemia (ALL). CD123, the α subunit of the interleukin-3 receptor, is overexpressed in ALL and is a potential therapeutic target. Here, we show that pivekimab sunirine (PVEK), a recently developed ADC comprising the CD123-targeting antibody, G4723A, and the cytotoxic payload, DGN549, was highly effective in vivo against a large panel of pediatric ALL patient-derived xenograft (PDX) models ( = 39).
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
School of Environment, Tsinghua University, Beijing 100084, China.
Overexploiting ecosystems to meet growing food demands threatens global agricultural sustainability and food security. Addressing these challenges requires solutions tailored to regional agro-ecological boundaries (AEBs) and overall agro-ecological risks. Here, we propose a globally consistent and regionally adapted approach for quantifying regional AEBs.
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