Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Accessibility of simulated submillimetre vessels for training supermicrosurgeons is limited by cost and access to micro laboratory facilities. Common simulation techniques include in vivo rat mesenteric artery, ex-vivo cryopreserved artery, ex-vivo chicken wing or thigh and synthetic models such as silicone tubing. The lowest cost and most readily accessible of these is the chicken wing model (Hayashi et al., 2018). None of these models follow the principles of NC3R humane animal research (replacement, reduction and refinement) and so we present a modified latex surgical glove model which provides a range of sub-millimetre vessels. Ten simulated vessels were made of each size and then divided and examined under a microscope. A calibrated vessel size ruler was used to visually assess the size. Average vessel sizes of 0.4 mm, 0.6 mm and 1.0 mm were achieved. The equipment required to make these is readily available in most hospitals. We find this a low cost, accessible method of creating simulated non-meat supermicrosurgical vessels for training.
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Source |
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http://dx.doi.org/10.1016/j.bjps.2024.12.005 | DOI Listing |
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