Technological advancements have intensified the demand for effective counterfeiting protection. This work presents multi-level security features in a (Ca,Zn)TiO:Pr,Er phosphor. A dual doping strategy synergistically results in dynamically changing luminescence emission. Upon excitation at 379 nm, the sample exhibits a yellowish green emission and exhibits deep red persistent emission for 12 minutes.
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http://dx.doi.org/10.1039/d4cc05643d | DOI Listing |
Front Oncol
January 2025
Department of Oncology, Georgetown University Medical Center, Washington, DC, United States.
Cancer's epigenetic landscape, a labyrinthine tapestry of molecular modifications, has long captivated researchers with its profound influence on gene expression and cellular fate. This review discusses the intricate mechanisms underlying cancer epigenetics, unraveling the complex interplay between DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs. We navigate through the tumultuous seas of epigenetic dysregulation, exploring how these processes conspire to silence tumor suppressors and unleash oncogenic potential.
View Article and Find Full Text PDFMed Res Rev
January 2025
Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.
Targeted protein degradation (TPD) has emerged as a significant therapeutic approach for a variety of diseases, including cancer. Advances in TPD techniques, such as molecular glue (MG) and lysosome-dependent strategies, have shown substantial progress since the inception of the first PROTAC in 2001. The PROTAC methodology represents the forefront of TPD technology, with ongoing evaluation in more than 20 clinical trials for the treatment of diverse medical conditions.
View Article and Find Full Text PDFMetab Eng
January 2025
Biochemistry, Molecular, Cellular, and Developmental Graduate Group, University of California, Davis, Davis, CA, 95616, USA; Department of Chemistry, University of California, Davis, Davis, CA, 95616, USA. Electronic address:
D-allose is a rare monosaccharide, found naturally in low abundances. Due to its low-calorie profile and similar taste to sucrose, D-allose has the potential to become an ideal sugar substitute. D-allose also displays unique properties and health benefits that can be applied to various fields, including food and medicine.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Huzhou Key Laboratory of Materials for Energy Conversion and Storage, College of Science, Huzhou University, Huzhou 313000, China. Electronic address:
1550 nm-responsive upconversion luminescence (UCL) has attracted increasing attention due to its potential applicability in a new generation of bio-probes and photonic devices. However, regulating multi-color UCL with pump power remains a challenge. In this work, through constructing the coupling between Er and Tm ions and suppressing the energy transfer upconversion process of Er ions, the response of UCL color in Gd(MoO):Er/Tm to pump power is enhanced significantly.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
January 2025
Research and Development Cell, and Parul Institute of Applied Sciences, Parul University, P.O. Limda, Ta.Waghodia, Dist. Vadodara, Gujarat-391760; India.
As Ugandans grapple with an increase in metabolic diseases, researchers are turning to their rich tradition of natural remedies. This review explores promising plants, such as Moringa oleifera, bridging the gap between the wisdom of Ugandan healers and modern science. Although these plants show potential, challenges remain.
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