Background: Research indicates that obesity can worsen the clinical manifestations of chronic obstructive pulmonary disease (COPD). Timely detection of COPD has the potential to enhance treatment results. This study seeks to investigate the association between a new metabolic indicator, the lipid accumulation product (LAP), and the risk of developing COPD.
Methods: The observational analysis employs data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2007 to 2016. Multivariate logistic regression was used to explore the association between LAP levels and COPD. Further analysis methods included subgroup analysis, smooth curve modeling, and threshold effect evaluation.
Results: Within the sample of 12,089 individuals, 1,072 were diagnosed with COPD. A positive correlation between LAP levels and COPD risk was identified through logistic regression analysis, even after controlling for potential confounders. The analyses by subgroup showed an enhanced association in participants without hypertension. The smooth curve fitting analysis highlighted particular saturation effects of LAP, with significant inflection points identified at 65.5278 and a P-value of 0.013.
Conclusion: This study's findings suggest that elevated LAP levels are associated with an increased risk of COPD. It is suggested that dietary modifications and exercise routines be implemented to mitigate COPD risk in those with higher LAP levels.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1186/s12890-024-03465-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Plant roots form associations with both beneficial and pathogenic soil microorganisms. While members of the rhizosphere microbiome can protect against pathogens, the mechanisms are poorly understood. We hypothesized that the ability to form a robust biofilm on the root surface is necessary for the exclusion of pathogens; however, it is not known if the same biofilm formation components required are necessary WCS365 is a beneficial strain that is phylogenetically closely related to an opportunistic pathogen N2C3 and confers robust protection against N2C3 in the rhizosphere.
View Article and Find Full Text PDFAssociation between lipid accumulation product and chronic obstructive pulmonary disease: a cross-sectional analysis.
BMC Pulm Med
January 2025
Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Background: Research indicates that obesity can worsen the clinical manifestations of chronic obstructive pulmonary disease (COPD). Timely detection of COPD has the potential to enhance treatment results. This study seeks to investigate the association between a new metabolic indicator, the lipid accumulation product (LAP), and the risk of developing COPD.
View Article and Find Full Text PDFThe effects and predictive values of novel anthropometric parameters on uric acid levels and hyperuricemia in adults.
Sci Rep
January 2025
Department of Cardiovascular Medicine, Jiangsu Provincial People's Hospital Group Taihu Sanatorium of Jiangsu Province, Wuxi, 214086, China.
Novel anthropometric indices are more closely related to metabolic abnormalities than traditional anthropometric indices. Fewer studies have been conducted based on the relationship between novel anthropometric indicators and hyperuricemia. This study was to analyze the serum uric acid (SUA) levels of adults and the relationship between hyperuricemia and these new indicators in Su-Wuxi-Chang area of China, in order to provide a theoretical basis for the management of SUA levels in patients with hyperuricemia.
View Article and Find Full Text PDFAutomating excellence: A breakthrough in emergency general surgery quality benchmarking.
J Trauma Acute Care Surg
January 2025
From the Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery (L.A.P., Z.M., J.M., B.H., T.W.C., L.N.H., A.B., L.A., J.J.D., J.E.S.), UC San Diego School of Medicine, San Diego, California; and Division of Acute Care Surgery, Department of Surgery (A.E.L.), University of Missouri School of Medicine, Columbia, Missouri.
Article Synopsis
- Developed an automated electronic health record (EHR)-linked registry to assess risks in emergency general surgery (EGS) using modified scoring systems, aiming to improve efficiency and accuracy.
- Analyzed data from 177 patients who underwent emergent surgeries between 2018-2023, finding an 18% mortality rate and 45% complication rate within 30 days post-surgery.
- The new scores (mESS and mPOTTER) showed strong agreement with traditional risk calculators, indicating potential for better quality assessment in EGS.
Schizophrenia Following Early Adolescence Prodrome: A Neurodevelopmental Subtype With Autism-like Sensorimotor and Social Cognition Deficits.
Schizophr Bull
January 2025
Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Team "Pathophysiology of psychiatric disorders", Institut de psychiatrie, CNRS GDR 3557, 75014 Paris, France.
Article Synopsis
- The study investigates how early-adolescence prodromes in schizophrenia (SCZ) relate to social cognition deficits and sensorimotor impairments, comparing them to autism spectrum disorders (ASD).
- It involves four groups: ASD, SCZ with early-adolescence prodromes (under 15), SCZ with late-adolescence prodromes (over 15), and a control group, analyzing their social cognition and neurological soft signs (NSS).
- Findings indicate that SCZ with early prodromes show similar social cognition impairments as those with ASD, highlighting that age of prodrome onset plays a critical role in understanding SCZ subgroups rather than just the onset of psychosis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!