Background: The present study aimed to explore the threshold-effect association of serum ferritin levels with type 2 diabetes mellitus (T2DM) and prediabetes mellitus in Chinese adults.
Methods: A total of 8365 people from CHNS a cross-sectional survey in 2009 were finally included. The biomarker data, including major cardiovascular biomarkers and important nutrition biomarkers were collected. The association of serum ferritin levels with T2DM and prediabetes mellitus were assessed by using restricted cubic spline function combined with multivariate logistic regression model.
Results: The mean age of the study subjects was 50.3 years, and 46.5% were men. The risk of T2DM and prediabetes mellitus increased when the ferritin level was greater than 140 ng/ml. The OR(OR = 0.59, 95% CI, 0.35-0.98)was lowest between 40 to < 60 ng/ml in men with prediabetes mellitus. The OR(OR = 0.61, 95% CI, 0.41-0.90)was lowest between 20 to < 40 ng/ml in women with prediabetes mellitus. Serum ferritin levels and OR value of women younger than 50 years old are lower than those of other participants.
Conclusions: There is a correlation between ferritin levels and pathoglycemia, with women under 50 years old having a lower risk for the same ferritin level, and maintaining low levels of ferritin can reduce the risk of developing diabetes mellitus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1186/s12902-024-01822-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Comparison of the efficacy and safety between high-dose intravenous iron and oral iron in treating iron deficiency anemia: a multicenter, prospective, open-label, randomized controlled study].
Zhonghua Xue Ye Xue Za Zhi
December 2024
Soochow Hopes Hematonosis Hospital, Suzhou 215128, China The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Collaborative Innovation Center of Hematology, Suzhou 215006, China.
This study aimed to compare the efficacy and safety between high-dose intravenous iron and oral iron in treating iron deficiency anemia (IDA) . This prospective randomized controlled study (1∶1) enrolled 338 patients with IDA at The First Affiliated Hospital of Soochow University, Suzhou Hongci Hematology Hospital, and Huai'an Second People's Hospital from June 1, 2022, to January 19, 2024. Of all the patients, 169 received high-dose intravenous iron therapy and 169 received oral iron treatment for 12 weeks of observation.
View Article and Find Full Text PDFClinical characteristics and risk factors for pneumonia in children.
Front Pediatr
December 2024
Department of Pediatrics, Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Background: () is one of the most common pathogens of community-acquired pneumonia (CAP) in children. Although pneumonia (MPP) is considered a self-limiting disease, severe MPP (SMPP) occurs in some cases. This study aims to analyze clinical features of MPP and to explore predictive indicators in the early stage of infection.
View Article and Find Full Text PDFThreshold-effect of ferritin levels with pathoglycemia in Chinese adults: a cross-sectional study based on China health and nutrition survey data.
BMC Endocr Disord
January 2025
Department of Nutrition and Food Safety, School of Public Health, Xi'an Jiaotong University, Xi'an, 710061, China.
Background: The present study aimed to explore the threshold-effect association of serum ferritin levels with type 2 diabetes mellitus (T2DM) and prediabetes mellitus in Chinese adults.
Methods: A total of 8365 people from CHNS a cross-sectional survey in 2009 were finally included. The biomarker data, including major cardiovascular biomarkers and important nutrition biomarkers were collected.
The association of Helicobacter pylori infection with the risk of anemia in children: systematic review and meta-analysis.
BMC Infect Dis
January 2025
Department of Medical Laboratory Science, College of Medicine and Health Sciences, Jigjiga University, Jigjiga, Ethiopia.
Background: Children are among the most vulnerable groups for Helicobacter pylori (H. pylori) infection, which was linked with an increased risk of anemia. H.
View Article and Find Full Text PDFThe diverse microbiota of the intestine is expected to benefit the host, yet the beneficial metabolites derived from the microbiota are still poorly understood. Enterobactin (Ent) is a well-known secreted iron-scavenging siderophore made by bacteria to fetch iron from the host or environment. Little was known about a positive role of Ent until a recent discovery in the nematode C.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!