Expression of Somatostatin Receptors in the Small Intestine during Postnatal Ontogenesis.

Bull Exp Biol Med

Yaroslavl State Medical University, Ministry of Health of the Russian Federation, Yaroslavl, Russia.

Published: December 2024

The expression of somatostatin receptors (SSTRs) of types 1, 2, and 5 was studied in the small intestine of rats from different age groups (1, 10, 20, 30, 60 days, and 2-year-old) using Western blotting. The expression of SSTR1, SSTR2, and SSTR5 increased in the first 30 days of life, but decreased in older rats compared to 2-month-old animals. These findings suggest that there is differential expression of SSTRs during age-related development of the small intestine. Further studies will determine the role of individual SSTRs in the growth and development of target organs.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10517-025-06303-3DOI Listing

Publication Analysis

Top Keywords

small intestine
12
expression somatostatin
8
somatostatin receptors
8
expression
4
receptors small
4
intestine postnatal
4
postnatal ontogenesis
4
ontogenesis expression
4
receptors sstrs
4
sstrs types
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!