The 2024 Chinese hypertension guidelines has been recently issued by Chinese Hypertension League (CHL), joint with partner societies. Since the 2018 guidelines was released, amount of evidence accumulated, in favor of intensive blood pressure (BP) control. New drugs and devices, innovative concepts and new insights have been introduced into hypertension management. The hypertension control rate improved gradually in past 30 years, while the constantly increased population of hypertension and high-normal BP still brought huge burden in China. More efficient, precise and individualized strategies for BP control are needed. The new guidelines integrated the latest evidence from epidemiological studies and clinical trials, particularly included recent data from Chinese populations, together with new concept and insights of hypertension management from the globe. In brief, the 2024 Chinese hypertension guidelines insists on 140/90 mmHg as the office BP thresholds for hypertension diagnosis. Ambulatory or home BP monitoring are recommended as alternatives for diagnosis. Validated smart wearable devices are introduced for hypertension screening and monitoring. A combined BP level and CV risk -based treatment strategy is still adopted. A more aggressive BP target ( < 130/80 mmHg) is recommended for most, including those at high CV risk, if tolerable. Low-sodium and potassium-rich salt substitute and Chinese heart-healthy diet are recommended and sleep and mental health are added in addition to traditional life style changes. New drugs and more flexible combination protocols, and concise treatment algorithm are introduced. Management of hypertension in special populations are updated and specific phenotype, for instance morning and nocturnal hypertension are addressed.
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http://dx.doi.org/10.1038/s41440-024-02070-2 | DOI Listing |
Trends Endocrinol Metab
January 2025
Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of Hypertension, Chongqing, China; Chongqing Institute for Brain and Intelligence, Chongqing, China. Electronic address:
Primary aldosteronism (PA) is a common, salt-sensitive form of endocrine hypertension. Compared with essential hypertension (EH), PA is more susceptible to cardiorenal complications and metabolic risks. However, PA has a low screening rate and a poor response to mineralocorticoid receptor antagonists (MRAs).
View Article and Find Full Text PDFHigh blood pressure is a significant risk factor for cardiovascular diseases and is linked to an increased risk of mild cognitive impairment (MCI). The lack of effective treatments for these conditions highlights the urgent need for novel therapeutic approaches. Recent research suggests that the gut microbiota-brain-gut axis plays a crucial role in the pathogenesis of hypertension and MCI by regulating the nervous, endocrine, and immune systems.
View Article and Find Full Text PDFFront Cardiovasc Med
December 2024
Department of Hypertension, Henan Provincial People's Hospital, Zhengzhou, China.
Background: Previous studies suggest that frailty increases the risk of mortality, but the risk of cardiovascular disease (CVD) and all-cause mortality in Chinese community-dwelling older adults remains understudied. Our aim was to explore the effect of frailty on cardiovascular and all-cause mortality in older adults based on a large-scale prospective survey of community-dwelling older adults in China.
Methods: We utilized the 2014-2018 cohort of the Chinese Longitudinal Healthy Longevity Survey and constructed a frailty index (FI) to assess frailty status.
Front Endocrinol (Lausanne)
January 2025
Department of Endocrinology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Introduction: This study aims to explore the risk factors in the progression of gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM).
Material And Methods: Relevant studies were comprehensively searched from PubMed, Web of Science, Cochrane Library, and Embase up to March 12. Data extraction was performed.
Arch Esp Urol
December 2024
Obstetrics and Gynecology Department, Anhui Wannan Rehabilitation Hospital (The Fifth People's Hospital of Wuhu), 241000 Wuhu, Anhui, China.
Background: Urinary tract stones present significant health risks to pregnant women and their foetuses. However, the specific risk factors contributing to stone formation during pregnancy, particularly within the Chinese population, remain poorly understood. This retrospective survey aimed to identify demographic, clinical, and obstetric risk factors associated with urinary tract stones in pregnant women at a tertiary hospital in China.
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