Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet its assessment relies largely on patient-reported outcomes, which capture perception but not fluctuations over time. Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. This study investigates the relationship between sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue in participants with Parkinson's, Huntington's, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren's syndrome and inflammatory bowel disease. Over 4 weeks, participants wore an IMU and reported fatigue levels four times daily. Using mixed-effects models, associations were identified between fatigue and specific kinematic features, such as 5th and 95th percentiles of sit-to-stand performance, suggesting that fatigue alters the control and effort of movement. These kinematic features show promise as indicators for fatigue in these patient populations.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41746-024-01386-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association of real life postural transitions kinematics with fatigue in neurodegenerative and immune diseases.
NPJ Digit Med
January 2025
Department of Neurology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Kiel, Germany.
Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet its assessment relies largely on patient-reported outcomes, which capture perception but not fluctuations over time. Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. This study investigates the relationship between sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue in participants with Parkinson's, Huntington's, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren's syndrome and inflammatory bowel disease.
View Article and Find Full Text PDFBioinspired surface structures for added shear stabilization in suction discs.
Sci Rep
January 2025
John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, 02134, USA.
Many aquatic organisms utilize suction-based organs to adhere to diverse substrates in unpredictable environments. For multiple fish species, these adhesive discs include a softer disc margin consisting of surface structures called papillae, which stabilize and seal on variable substrates. The size, arrangement, and density of these papillae are quite diverse among different species, generating complex disc patterns produced by these structures.
View Article and Find Full Text PDFElectromyographic and kinematic characteristics of baseball players with yips exhibiting different types of dystonic movements: A two-case report.
Heliyon
January 2025
Center for Medical Sciences, Ibaraki Prefectural University of Health Sciences, Japan.
Article Synopsis
- The yips is a coordination issue in athletes, especially baseball players, tied to task-specific dystonia.
- This study focused on two baseball players displaying different yips symptoms, analyzing their throwing motions and muscle activity using advanced technology.
- It identified two types of dystonic movements: one involving excessive elbow flexion due to improper muscle contraction, and another featuring tremors from inconsistent muscle activity, emphasizing the need for personalized analysis in understanding and addressing yips symptoms.
Conceptual foundations of a REFRAME-based approach to discriminate across total knee implant designs based on the positions of functional centres of rotation.
Sci Rep
January 2025
Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Ludwig Maximilians University Munich, Munich, Germany.
In modern knee arthroplasty, surgeons increasingly aim for individualised implant selection based on data-driven decisions to improve patient satisfaction rates. The identification of an implant design that optimally fits to a patient's native kinematic patterns and functional requirements could provide a basis towards subject-specific phenotyping. The goal of this study was to achieve a first step towards identifying easily accessible and intuitive features that allow for discrimination between implant designs based on kinematic data.
View Article and Find Full Text PDFBiomechanical coordination and variability alters following repetitive movement fatigue in overhead athletes with painful shoulder.
Sci Rep
January 2025
Department of Sport Biomechanics, Faculty of Sports Sciences, Bu-Ali Sina University, Hamedan, Iran.
Most sports and leisure activities involve repetitive movements in the upper limb, which are typically linked to pain and discomfort in the neck and shoulder area. Movement variability is generally expressed by changes in movement parameters from one movement to another and is a time-dependent feature of repetitive activities. The purpose of this study was to examine the effect of repeated movement-induced fatigue on biomechanical coordination and variability in athletes with and without chronic shoulder pain (CSP).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!