This study utilizes the Breast Ultrasound Image (BUSI) dataset to present a deep learning technique for breast tumor segmentation based on a modified UNet architecture. To improve segmentation accuracy, the model integrates attention mechanisms, such as the Convolutional Block Attention Module (CBAM) and Non-Local Attention, with advanced encoder architectures, including ResNet, DenseNet, and EfficientNet. These attention mechanisms enable the model to focus more effectively on relevant tumor areas, resulting in significant performance improvements. Models incorporating attention mechanisms outperformed those without, as reflected in superior evaluation metrics. The effects of Dice Loss and Binary Cross-Entropy (BCE) Loss on the model's performance were also analyzed. Dice Loss maximized the overlap between predicted and actual segmentation masks, leading to more precise boundary delineation, while BCE Loss achieved higher recall, improving the detection of tumor areas. Grad-CAM visualizations further demonstrated that attention-based models enhanced interpretability by accurately highlighting tumor areas. The findings denote that combining advanced encoder architectures, attention mechanisms, and the UNet framework can yield more reliable and accurate breast tumor segmentation. Future research will explore the use of multi-modal imaging, real-time deployment for clinical applications, and more advanced attention mechanisms to further improve segmentation performance.
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http://dx.doi.org/10.1038/s41598-024-84504-y | DOI Listing |
Zhonghua Xue Ye Xue Za Zhi
December 2024
Institute of Hematology, Tongji Medical College Affiliated Union Hospital, Huazhong University of Science and Technology, Wuhan 430022, China.
Venous thromboembolism (VTE) is clinically manifested as deep vein thrombosis (DVT) and pulmonary embolism (PE). VTE is the third most prevalent vascular disease after coronary artery and cerebrovascular diseases. VTE is a multifactorial disease caused by the interaction of genetic and acquired risk factors.
View Article and Find Full Text PDFGeriatr Nurs
January 2025
Nanjing University of Chinese Medicine, Nanjing, PR China. Electronic address:
Background: Social isolation is a significant risk factor for depressive symptoms in older adults, with social support and resilience serving as protective factors. However, the mechanisms underlying this association are not well understood.
Methods: A cross-sectional survey was performed of 1020 participants (aged ≥ 60years) in the northern, central and southern parts of Jiangsu Province, China.
Ecotoxicol Environ Saf
January 2025
School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China; Clinical Epidemiology Unit, Qilu Hospital of Shandong University, Jinan, China; Clinical Research Center of Shandong University, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. Electronic address:
Background: The causal relationship between PM (particulate matter with an aerodynamic diameter ≤2.5 μm) and common mental disorders, along with its neuropathological mechanisms, remains unclear.
Methods: We used genome-wide association study datasets from the UK Biobank and Psychiatric Genomics Consortium to systematically investigate the causal relationship between PM and nine common psychiatric disorders using two-sample Mendelian randomization (TSMR) methods.
J Hazard Mater
January 2025
Institute of Chemical Technology, Vietnam Academy of Science and Technology, 1A TL29 Street, Thanh Loc Ward, District 12, HCM City, Viet Nam; Graduate University of Science and Technology, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay District, Hanoi, Viet Nam. Electronic address:
Whole-cell bioreactors equipped with external physico-chemical sensors have gained attention for real-time toxicity monitoring. However, deploying these systems in practice is challenging due to potential interference from unknown wastewater constituents with liquid-contacted sensors. In this study, a novel approach using a bioreactor integrated with a non-dispersive infrared CO₂ sensor for both toxicity detection and real-time monitoring of microbial growth phases was successfully demonstrated.
View Article and Find Full Text PDFJ Adv Res
January 2025
Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education and Key Laboratory of Basic Pharmacology of Guizhou Province and Laboratory Animal Centre, Zunyi Medical University, Zunyi, Guizhou, China. Electronic address:
Background: Neurodegenerative diseases (NDs) constitute a significant public health challenge, as they are increasingly contributing to global mortality and morbidity, particularly among the elderly population. Pathogenesis of NDs is intricate and multifactorial. Recently, post-transcriptional modifications (PTMs) of RNA, with a particular focus on mRNA methylation, have been gaining increasing attention.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!