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Redistribution of Residency Slots After Hospital Closures.
JAMA Intern Med
January 2025
Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
Unobtrusive Nighttime Movement Monitoring to Support Nursing Home Continence Care: Algorithm Development and Validation Study.
JMIR Nurs
December 2024
e-Media Research Lab/STADIUS, Department of Electrical Engineering, KU Leuven, Andreas Vesaliusstraat 13, Leuven, 3000, Belgium, +32 16377662.
Background: The rising prevalence of urinary incontinence (UI) among older adults, particularly those living in nursing homes (NHs), underscores the need for innovative continence care solutions. The implementation of an unobtrusive sensor system may support nighttime monitoring of NH residents' movements and, more specifically, the agitation possibly associated with voiding events.
Objective: This study aims to explore the application of an unobtrusive sensor system to monitor nighttime movement, integrated into a care bed with accelerometer sensors connected to a pressure-redistributing care mattress.
A feasibility model for restructuring the role of the hand surgeon taking call at a level I trauma center.
J Hand Microsurg
December 2024
Department of Plastic and Reconstructive Surgery, New York City Health and Hospitals/Jacobi, Albert Einstein College of Medicine, Bronx, NY, USA.
Background: The discrepancy between the volume of hand-related consults and the concurrent lack of specialized hand surgeons available continues to strain an overburdened system. Recent attention has focused on the redistribution of this workload towards management in the outpatient realm.
Methods: This is a retrospective review of hand consults for the plastic surgery service over summer and winter intervals at a Level I trauma center.
Mathematical multi-compartment modeling of chronic lymphocytic leukemia cell kinetics under ibrutinib.
iScience
December 2024
Institute of AI for Health, Helmholtz Munich - German Research Centre for Environmental Health, Neuherberg, Germany.
The Bruton tyrosine kinase inhibitor ibrutinib is an effective treatment for patients with chronic lymphocytic leukemia (CLL). While it rapidly reduces lymph node and spleen size, it initially increases the number of lymphocytes in the blood due to cell redistribution. A previously published mathematical model described and quantified those cell kinetics.
View Article and Find Full Text PDFLungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.
Nat Commun
November 2024
Institute of Lung Health and Immunity (LHI), Helmholtz Munich, Comprehensive Pneumology Center (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.
Targeted (nano-)drug delivery is essential for treating respiratory diseases, which are often confined to distinct lung regions. However, spatio-temporal profiling of drugs or nanoparticles (NPs) and their interactions with lung macrophages remains unresolved. Here, we present LungVis 1.
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