Motivation And Results: Crypt4GH-JS is a browser-ready implementation of the Crypt4GH file encryption standard written in JavaScript. While having minimal to no impact on data upload and download throughput this library enables on-the-fly encryption of arbitrary data in web applications, regardless of whether on the client or server side. As development moves more and more towards cloud-native applications, this library represents a significant step forward for flexible data security in the context of opaque cloud storage systems.
Availability And Implementation: Crypt4GH-JS can be installed via Node Package Manager(https://www.npmjs.com/package/crypt4gh_js) or through its public GitHub Repository (https://github.com/fathelen/crypt4ghJS), where the source code is available. Crypt4GH-JS can be tested in the browser using our demonstration website, which can be found at: https://fathelen.github.io/crypt4ghJS/.
Supplementary Information: Supplementary data are available at Bioinformatics online.
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http://dx.doi.org/10.1093/bioinformatics/btae763 | DOI Listing |
Neurophysiol Clin
January 2025
Neuroscience and Human Genetics Department, Meyer Children's Hospital IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies, EpiCARE, viale Pieraccini 24, 50139, Florence, Italy; Neurofarba Department, University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Stereo-EEG is not just a diagnostic examination but a complex methodology, requiring an accurate synthesis of many data (anatomical, clinical, neurophysiological, cognitive, metabolic, and genetic). The implantation scheme is decided based on a hypothesis (or hypotheses) of epileptogenic zone localization. Subsequently, intracerebral electrical stimulation is used to define the extent of highly functional cortical regions and to reproduce the clinical symptoms and signs associated with seizures.
View Article and Find Full Text PDFNutr Res
December 2024
Faculty of Medicine, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Faculty of Medicine, Clinical Research Institute, American University of Beirut, Beirut, Lebanon.
While low dietary quality has been linked to poor mental health, evidence on more direct relations of specific dietary quality indicators, namely degrees of food processing, with mental health disorders remains limited. This study aims to investigate the association between food groups' intakes, defined based on their degree of food processing, with depression and anxiety symptoms in a sample of Lebanese adults. We hypothesized that higher intakes of ultra-processed foods (UPF) will be related to higher risk of depression and anxiety while an opposite association will be observed for unprocessed or minimally processed foods (MPF).
View Article and Find Full Text PDFGynecol Oncol
January 2025
GOG Foundation, Florida Cancer Specialists and Research Institute, West Palm Beach, FL 33401, United States of America. Electronic address:
Objective: Therapeutic interventions for epithelial ovarian cancer (EOC) have increased greatly over the last decade but improvements outside of biomarker selected therapies have been limited. There remains a pressing need for more effective treatment options that can prolong survival and enhance the quality of life of patients with EOC. In contrast to the significant benefits of immunotherapy with immune checkpoint inhibitors (CPI) seen in many solid tumors, initial experience in EOC suggests limited efficacy of CPIs monotherapy.
View Article and Find Full Text PDFAm J Ther
January 2025
Department of Medicine, Long Island Jewish Forest Hills (Northwell Health), Forest Hills, NY.
Background: West Nile virus (WNV), although underdiagnosed, is the most common mosquito-borne disease and the second most common cause of viral encephalitis in the United States. Fewer than 1% of those infected develop neuroinvasive disease.
Methods: We present a cluster of 3 cases of neuroinvasive WNV that occurred between August and September 2023 and a review of the literature for neurologic involvement with this virus.
Afr J Reprod Health
December 2024
Changchun Sci-Tech University, JiLin ChangChun 130600, China.
This study assesses gender inequality in education and employment in BRICS (Brazil, Russia, India, China, and South Africa) countries between the 2000 and 2021, using data from the World Bank database. A descriptive data analysis was carried out as well as graphical representations to compare among countries. The results showed that that female education achieved significant success, especially at secondary and tertiary levels, through specific policies including financial support and affirmative actions.
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