AI Article Synopsis

  • The review discusses current treatment methods and strategies for managing lower urinary tract symptoms (LUTS) linked to treatments like transurethral resection and intravesical therapy.
  • Recent findings highlight that while there's limited research, some oral agents and new therapies show promise in alleviating LUTS associated with intravesical treatments, such as phenazopyridine and beta-3 agonists.
  • The review emphasizes the need for more research to validate these treatments and to develop effective strategies for managing LUTS in patients undergoing various intravesical therapy regimens.

Article Abstract

Purpose Of Review: This narrative review aims to report upon the existing treatment evidence and strategies for managing lower urinary tract symptoms (LUTS) during treatment, including transurethral resection and intravesical therapy. This review also attempts to examine novel approaches to mitigate treatment-related lower urinary tract symptoms and improve treatment adherence.

Recent Findings: There is sparse but promising evidence in improving LUTS secondary to intravesical therapy. Oral agents including phenazopyridine and hyaluronic acid, Bacillus Calmette-Guerin dose reduction, and emerging therapies including beta-3 agonists as well as Onabotulinumtoxin A injections all have demonstrated encouraging improvement in LUTS in limited research. Although recent literature explores new medications and potential strategies for managing intravesical therapy-related LUTS, further research is required to establish efficacy and new consensus on treatment strategies. Further research is also required to establish effective LUTS mitigation strategies with other emerging intravesical therapy regimens.

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http://dx.doi.org/10.1007/s11934-024-01250-4DOI Listing

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