Involvement of the temporomandibular joint (TMJ) in patients with juvenile idiopathic arthritis (JIA) has been increasingly reported, affecting up to 87% of cases. This involvement generally occurs after the diagnosis of JIA has been established; however, in the authors' cases, as in a few others documented in the literature, patients presented with isolated TMJ arthritis as the sole joint involvement. The authors performed a narrative literature review on TMJ involvement in JIA and reported 2 cases that presented with isolated TMJ arthritis as the initial manifestation of JIA. Although isolated TMJ involvement may be rare, it can lead to severe complications, such as complete loss of TMJ function. Thus, clinicians should be aware of this potential presentation to conduct necessary investigations and provide appropriate treatment.

Download full-text PDF

Source
http://dx.doi.org/10.1097/SCS.0000000000011000DOI Listing

Publication Analysis

Top Keywords

isolated tmj
12
juvenile idiopathic
8
idiopathic arthritis
8
presented isolated
8
tmj arthritis
8
tmj involvement
8
tmj
6
arthritis
5
involvement
5
isolated
4

Similar Publications

Isolated Temporomandibular Arthritis as Presentation of Juvenile Idiopathic Arthritis.

J Craniofac Surg

January 2025

Rheumatology Unit, Department of Childhood and Developmental Medicine, ASST Fatebenefratelli-Sacco, Milano, MI.

Involvement of the temporomandibular joint (TMJ) in patients with juvenile idiopathic arthritis (JIA) has been increasingly reported, affecting up to 87% of cases. This involvement generally occurs after the diagnosis of JIA has been established; however, in the authors' cases, as in a few others documented in the literature, patients presented with isolated TMJ arthritis as the sole joint involvement. The authors performed a narrative literature review on TMJ involvement in JIA and reported 2 cases that presented with isolated TMJ arthritis as the initial manifestation of JIA.

View Article and Find Full Text PDF

Proliferative behaviours of CD90-expressing chondrocytes under the control of the TSC1-mTOR/PTHrP-nuclear localisation segment pathway.

Osteoarthritis Cartilage

December 2024

Department of Oral Anatomy and Physiology and TMD, College of Stomatology, the Fourth Military Medical University, Xi'an, China; Department of Oral anatomy and Physiology and TMD, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China. Electronic address:

Objective: Some cells in temporomandibular joint (TMJ) cartilage undergo proliferation in response to negative pressure, which can be induced in vivo by creating bilateral anterior elevation (BAE). TMJ cartilage harbours CD90-expressing cells, and CD90 expression increases under certain controlled conditions. The parathyroid hormone-related peptide (PTHrP) nuclear localisation segment (NLS) promotes chondrocyte proliferation, and mammalian target of rapamycin (mTOR) signalling plays a regulatory role in promoting PTHrP transcription.

View Article and Find Full Text PDF

BMSC Derived Exosomes Attenuate Apoptosis of Temporomandibular Joint Disc Chondrocytes in TMJOA via PI3K/AKT Pathway.

Stem Cell Rev Rep

November 2024

Department of Orthodontics, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, 510182, Guangdong, China.

Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) are crucial means of intercellular communication and can regulate a range of biological processes by reducing inflammation, decreasing apoptosis and promoting tissue repair. We treated temporomandibular joint (TMJ) disc chondrocytes with TNF-α and performed local injection of sodium iodoacetate (MIA) in the TMJ of rats to establish in vitro and in vivo models of TMJ osteoarthritis (TMJOA). BMSC-Exos were isolated and extracted to evaluate their proliferation and trilineage differentiation abilities, and their antiapoptotic and chondroprotective effects were assessed.

View Article and Find Full Text PDF
Article Synopsis
  • Rheumatoid arthritis is an autoimmune disease that primarily causes swelling in the joints, especially in a symmetrical pattern in the extremities, but can also affect multiple organ systems.
  • Scleritis (inflammation of the eye) and temporomandibular disorder (TMD) can be less recognized symptoms of rheumatoid arthritis.
  • Recognizing the connection between these symptoms and autoimmune diseases can lead to earlier diagnosis and more personalized treatment plans to manage the disease effectively.
View Article and Find Full Text PDF

Preauricular versus intraoral condylectomy for the treatment of unilateral condylar hyperactivity.

Br J Oral Maxillofac Surg

November 2024

Maxillofacial Surgery Department, Academic Hospital of Udine, Department of Medicine, University of Udine, Italy.

In this study we retrospectively reviewed our clinic's treatment of unilateral condylar hyperactivity (UCH). We used computer-guided proportional condylectomy, which was conducted both through preauricular and intraoral approaches, then analysed the advantages and disadvantages of the two techniques. A computer-guided treatment algorithm is also presented.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!