AI Article Synopsis
- Bone implants made from biobased and biodegradable polyester composites are gaining popularity for effectively treating bone defects due to their good mechanical properties and ability to break down naturally.
- Bone tissue engineering (BTE) plays a crucial role by mimicking the natural bone environment, using composite scaffolds to promote and accelerate the healing process.
- The review highlights recent strategies by researchers to enhance the physical properties of BTE scaffolds and discusses the advantages of 3D printing technology while addressing future challenges for clinical applications.
Article Abstract
Transplantation of bone implants is currently recognized as one of the most effective means of treating bone defects. Biobased and biodegradable polyester composites combine the good mechanical and degradable properties of polyester, thereby providing an alternative for bone implant materials. Bone tissue engineering (BTE) accelerates bone defect repair by simulating the bone microenvironment. Composite scaffolds support bone formation and further accelerate the process of bone repair. The introduction of 3D printing technology enables the preparation of scaffolds to be more precise, reproducible, and flexible, which is a very promising development. This review presents the physical properties of BTE scaffolds and summarizes the strategies adopted by domestic and international scholars to improve the properties of scaffolds based on biobased and biodegradable polyester/ceramic composites in recent years. In addition, future development prospects in the field and the challenges of expanding production in clinical applications are presented.
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| http://dx.doi.org/10.1021/acsami.4c15719 | DOI Listing |
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