AI Article Synopsis
- Localized bladder amyloidosis is a rare condition that can be mistaken for a bladder tumor, with only over 200 cases documented.
- A 67-year-old woman experienced painless blood in urine, leading to tests that suggested bladder amyloidosis, including a Congo red staining potentially indicating the presence of amyloid.
- The excised tissue from her procedure showed unexpected pink-staining patterns but did not confirm amyloidosis through Congo red staining, highlighting the importance of thorough evaluation for diagnosis despite negative results.
Article Abstract
Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696844 | PMC |
| http://dx.doi.org/10.1016/j.eucr.2024.102902 | DOI Listing |
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