Background: There has been a growing body of research demonstrating that thigh circumference is closely associated with the development of various chronic disease. However, limited evidence has been obtained regarding the relationship between thigh circumference and sarcopenia.
Objective: The aim of this study was to investigate the relationship between thigh circumference and sarcopenia, and explore the potential role of thigh circumference for sarcopenia screening among community-dwelling older adults.
Methods: The investigation was carried out in six rural communities located in northwestern China with participants aged ≥60 years old. We collected variables related to sarcopenia, including function, muscle mass, and strength. The thigh circumference was categorized into four groups based on quartiles, with the first quartile (≤46.65 cm); the second quartile (46.66-48.50 cm); the third quartile (48.51-50.55 cm); and the fourth quartile (>50.55 cm). The associations and screening effect were estimated with multivariate logistics regression and ROC curves.
Results: Of the 1000 participants aged 70.72 ± 4.68 years. Compared with the first quartile (≤46.65 cm), the odds ratios for the second, third, and fourth quartiles of thigh circumference were 0.465 (95%CI: 0.281-0.770, p = 0.003), 0.199 (95%CI: 0.097-0.407, p < 0.001), and 0.059 (95%CI: 0.016-0.220, p < 0.001), respectively. The regression results were consistent across different sexes. The AUC and cutoff values of thigh circumference for sarcopenia were 0.873 (95 % CI 0.836-0.909, p < 0.001) and 48.83 cm for men and 0.861 (95 % CI 0.822-0.900, p < 0.001) and 46.78 cm for women. There was a positive correlation between thigh circumference and skeletal muscle mass (r = 0.747, p < 0.001), hand grip strength (r = 0.337, p < 0.001), and gait speed (r = 0.142, p < 0.001), while a negative correlation was observed with five-times-sit-to-stand test (r = -0.073, p = 0.021).
Conclusion: There was a negative correlation between thigh circumference and sarcopenia, suggesting that thigh circumference may serve as a potential useful indicator for sarcopenia screening in the elderly.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697553 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2024.e39322 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long-Term Follow-Up After the Charles Procedure: Possibilities for Minimally Invasive Reconstructive Lymphedema Surgery With Lymphaticovenous Anastomosis: A Report of Four Cases.
Microsurgery
January 2025
Plastic and Reconstructive Surgery, Department of Surgery, Hospital of Divine Savior, Vienna, Austria.
The Charles procedure (CP) is a potentially devastating treatment; however, in cases of an end stage of untreated or improperly treated lymphedema, it is the ultimate surgical therapy. As a life-saving solution, it quickly relieves patients with giant, hypertrophic extremities, mostly in ambulation and hygiene maintenance. Nevertheless, long-term results may disappoint both doctors and patients, who struggle with social stigma, the need for lifelong compression, massive lymphoedema in the distal parts of the feet, badly fitting shoes, excessive skin fibrosis, severe keratinization of skin-grafted surfaces, periodic lymphorrhea from the resected areas, or acute and chronic inflammation.
View Article and Find Full Text PDFThe value of nonenhanced magnetic resonance imaging (MRI) in the grading of primary lower extremity lymphedema.
J Vasc Surg Venous Lymphat Disord
January 2025
Department of Radiology, Beijing Shijitan Hospital, Capital Medical University, China. Electronic address:
Objective: The International Society of Lymphology (ISL) proposed a grading standard for lymphedema in 2020 based on the percent increase in the volume of the affected limb compared to that of the healthy limb. However, this method is cumbersome and time-consuming to measure and calculate, and a standardized formula across different institutions is not available. Therefore, the aim of this study was to investigate the value of nonenhanced MRI for grading primary lower extremity lymphedema (PLEL).
View Article and Find Full Text PDFComparing different timings of tourniquet application in total knee arthroplasty: effects on postoperative pain and bone cement interface.
J Orthop Surg Res
January 2025
Department of Orthopaedics, FuyangHospital of Anhui Medical University, Fuyang, Anhui, China.
Objective: This study aims to elucidate the impact of varying tourniquet application timings on postoperative pain and the bone cement interface following TKA.
Method: Patients who underwent TKA in our department between March 2021 and July 2023 were included in this study. They were randomly assigned to three groups: Group 1 used tourniquets throughout the operation, Group 2 applied tourniquets before the osteotomy, and Group 3 applied tourniquets after completing the osteotomy.
Predicting Body Fat Percentage from Anthropometric Measurements in Asian Athletes.
J Sci Sport Exerc
November 2024
Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47403, USA.
Purpose: Researchers have predicted body fat percentage (BF%), as indicated by dual energy X-ray absorptiometry (DXA), from skinfold thicknesses in North American and European athletes, but not athletes from other regions. We sought to estimate an equation to predict BF% in elite Asian athletes from their skinfold thickness and girth measurements, with DXA as a reference method.
Methods: We collected data from two samples of athletes on Singaporean national teams.
Sonographic and Anthropometric Measurements for Body Composition and Their Relationship with Functioning in Adolescent Obesity.
Klin Padiatr
January 2025
Physical and Rehabilitation Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Obesity is one of the most common chronic diseases seen in children and adolescents. This study aims to examine the impact of obesity on body composition, assessed by sonographic and anthropometric measurements, and health-related quality of life (HRQoL) in adolescents.Anthropometric measurements, sonographic measurements of subcutaneous fat, quadriceps muscle, Achilles tendon thickness, and HRQoL were performed in children between 12-18 years of age.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!