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Article Abstract
The crystal structures of (±)-mandelamide, -mandelamide, and enantioenriched mandelamide (94 : 6 ) were determined. Diastereomeric cocrystal pairs of -mandelamide with both enantiomers of mandelic acid and proline were synthesized. The diastereomeric cocrystal pairs of -mandelamide with /-mandelic acid form 1:1 cocrystals in each case, while the diastereomeric cocrystal pairs of -mandelamide with proline have different stoichiometries. Preliminary investigation of this diastereomeric cocrystal system for chiral resolution shows promise.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697332 | PMC |
| http://dx.doi.org/10.1021/acs.cgd.3c01513 | DOI Listing |
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