AI Article Synopsis
- Near-infrared-II (NIR-II) imaging is an advanced technique that enhances deep anatomical visualization by reducing issues like autofluorescence and tissue absorption.
- Current methods for creating NIR-II nanoprobes are inefficient, requiring significant time and effort, which calls for a quicker synthesis method.
- The study introduces DNA-templated silver nanoclusters (Ag NCs) that can be produced in just 2 minutes and are small enough to penetrate muscle tissue, making them effective for studying metabolic pathways through NIR-II imaging after intramuscular injection.
Article Abstract
Near-infrared-II (NIR-II) imaging has emerged as a powerful technique for high-resolution visualization of deep anatomical features, benefiting from minimized autofluorescence, diminished optical scattering, and absorption of tissue. However, the current synthesis of NIR-II nanoprobes is a time-consuming, labor-intensive process with low yields, highlighting the need for an efficient and rapid synthesis approach instead. Herein, we report DNA-templated silver nanoclusters (Ag NCs) with NIR-II emission that can be rapidly synthesized via a simple one-spot process within 2 min. The Ag NCs are about 1.6 nm in size, making it easy for them to enter into the capillaries of muscle tissue. NIR-II imaging results indicate that the Ag NCs we designed are promising probes for studying the metabolic pathways of nanoprobes after intramuscular injection. Therefore, it is expected that Ag NCs with ultrafast room temperature synthesis, excellent NIR-II emission, and ultrasmall size will be ideal probes for biological applications.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.nanolett.4c05525 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!