Purpose: Return to work (RTW) has been understudied in Asian women with cancer, despite the increasing number of breast cancer survivors (BCS). This study examined RTW among Korean BCS, exploring its associations with cancer-related fatigue, quality of sleep, mental adjustment, and psychosocial factors.
Methods: This cross-sectional study recruited BCS from a hospital, a breast cancer support group, and an online community in Korea between July and August 2019. We collected data on levels of fatigue, fatigability, quality of sleep, mental adjustment, and quality of working life. The analysis included data from 135 respondents who were employed prior to their cancer diagnosis. Descriptive statistics and multiple logistic regression analyses were conducted.
Results: Although all participants were employed prior to diagnosis, only 57% remained employed afterward. Participants who returned to work reported significant levels of subjective fatigue (102.48±39.84), physical fatigability (28.14±11.34), borderline poor sleep quality (8.57±4.11), anxious preoccupation (23.33±4.54), and low satisfaction with quality of working life (39.68±21.51). Marital status (odds ratio [OR], 3.34; p=.027), time since breast cancer diagnosis (OR, 2.85; p=.028), anxious preoccupation (OR, 0.89; p=.021), and quality of working life (OR, 1.04; p=.010) were found to be predictors of RTW, explaining 34% of the variance.
Conclusion: It is critical to address RTW-related difficulties in Korean BCS, and future RTW interventions should target cancer-related fatigue, anxious preoccupation, and quality of working life. Physical and psychosocial support is essential for BCS and their successful RTW.
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http://dx.doi.org/10.4069/whn.2024.12.10 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11700720 | PMC |
East Mediterr Health J
December 2024
Department of Radiology, King Abdulaziz University, Jeddah, Saudi Arabia.
Pharm Dev Technol
January 2025
Department of Pharmacy, School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029, China.
In this paper, the pH-sensitive targeting functional material NGR-poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate (NGR-PEtOz-CHMC, NPC) modified quercetin (QUE) liposomes (NPC-QUE-L) was constructed. The structure of NPC was confirmed by infrared spectroscopy (IR) and nuclear magnetic resonance hydrogen spectrum (H-NMR). Pharmacokinetic results showed that the accumulation of QUE in plasma of the NPC-QUE-L group was 1.
View Article and Find Full Text PDFJ Med Econ
January 2025
UNESCO-TWAS, The World Academy of Sciences, Trieste, Italy.
Aim: Dynamic cancer control is a current health system priority, yet methods for achieving it are lacking. This study aims to review the application of system dynamics modeling (SDM) on cancer control and evaluate the research quality.
Methods: Articles were searched in PubMed, Web of Science, and Scopus from the inception of the study to November 15th, 2023.
Int J Surg
January 2025
Computer Science and Technology, Harbin Institute of Technology (Shenzhen), Shenzhen, China.
Detection of biomarkers of breast cancer incurs additional costs and tissue burden. We propose a deep learning-based algorithm (BBMIL) to predict classical biomarkers, immunotherapy-associated gene signatures, and prognosis-associated subtypes directly from hematoxylin and eosin stained histopathology images. BBMIL showed the best performance among comparative algorithms on the prediction of classical biomarkers, immunotherapy related gene signatures, and subtypes.
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