AI Article Synopsis
- Technological innovations in genomics have enabled large sequencing projects and new biological insights in cancer, leading to the rise of liquid biopsy biomarkers.
- Despite progress in precision oncology, challenges remain due to cancer's complexity and variability, impacting effective treatment strategies.
- Advanced imaging technologies are being developed to enhance early detection and treatment options, but there are obstacles to their wider implementation in clinical settings that must be addressed.
Article Abstract
Technological innovations in genomics and related fields have facilitated large sequencing efforts, supported new biological discoveries in cancer, and spawned an era of liquid biopsy biomarkers. Despite these advances, precision oncology has practical constraints, partly related to cancer's biological diversity and spatial and temporal complexity. Advanced imaging technologies are being developed to address some of the current limitations in early detection, treatment selection and planning, drug delivery, and therapeutic response, as well as difficulties posed by drug resistance, drug toxicity, disease monitoring, and metastatic evolution. We discuss key areas of advanced imaging for improving cancer outcomes and survival. Finally, we discuss practical challenges to the broader adoption of precision imaging in the clinic and the need for a robust translational infrastructure.
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| http://dx.doi.org/10.1016/S1470-2045(24)00395-4 | DOI Listing |
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