Background: The aim of this study was to evaluate the correlation of the volume and minimum axial area (MAA) measurements between different upper and lower boundaries used for oropharyngeal airway assessment.
Methods: Cone Beam Computed Tomography (CBCT) scans of 49 subjects taken for pre-orthognathic surgical planning were obtained retrospectively from the archives (n = 49; 32 females, 17 males; mean age = 20.9 ± 5.22). Volume and MAA of the oropharyngeal airway were measured in 32 different airway segmentations created with four different upper and eight different lower boundaries using the Dolphin3D (Dolphin Imaging & Management Solutions, Chatsworth, California, ABD) software. All measurements were performed by the same examiner and were repeated 2 weeks apart. The correlation between the measurements was evaluated with the Pearson correlation test. Intra-observer reliability was calculated with the intra-class correlation coefficient.
Results: Volume and MAA showed excellent intra-observer reliability (0.997 and 0.999 intraclass correlation coefficients, respectively) and a high level of positive correlation (r = 0.896-0.999, and r = 0.859-1.00, respectively) for all the measurements.
Conclusions: All measurements between different lower and upper boundaries showed a high correlation. It was found that the lower and upper limits assessed in this study can be used safely in future upper airway studies according to the study design.
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http://dx.doi.org/10.1186/s12903-024-05402-3 | DOI Listing |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699794 | PMC |
Ren Fail
December 2025
Department of Nephrology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guangdong Province, China.
Background: Acute kidney injury (AKI) is a common complication in critically ill patients, with approximately 5% requiring continuous renal replacement therapy (CRRT). This study investigated the relationship between mean arterial pressure (MAP) and 28- and 90-day mortality in critically ill AKI patients treated with CRRT.
Methods: This secondary analysis of a bicenter, retrospective, observational study included patients with AKI who were treated with CRRT from January 2009 to September 2016.
J Anim Sci Biotechnol
January 2025
Department of Animal Science, University of Arkansas, Fayetteville, AR, USA.
Background: Sow longevity and reproductivity are essential in the modern swine industry. Although many studies have focused on the genetic and genomic factors for selection, little is known about the associations between the microbiome and sows with longevity in reproduction.
Results: In this study, we collected and sequenced rectal and vaginal swabs from 48 sows, nine of which completed up to four parities (U4P group), exhibiting reproductive longevity.
Diabetes Obes Metab
January 2025
Department of Hypertension and Vascular Disease, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Aims: Previous studies have shown that eGDR and TyG, as indicators of insulin resistance (IR), were key risk factors for cardiovascular disease (CVD). Our study further explored the relationship between eGDR change and new-onset CVD, and compared the predictive value of eGDR change, eGDR and TyG.
Materials And Methods: A total of 2895 participants without CVD at baseline from the China Health and Retirement Longitudinal Study (CHARLS) were included, using K-means clustering and cumulative eGDR to measure eGDR change between 2012 and 2015.
Acta Neuropathol Commun
January 2025
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Recent genomic studies have allowed the subdivision of intracranial ependymomas into molecularly distinct groups with highly specific clinical features and outcomes. The majority of supratentorial ependymomas (ST-EPN) harbor ZFTA-RELA fusions which were designated, in general, as an intermediate risk tumor variant. However, molecular prognosticators within ST-EPN ZFTA-RELA have not been determined yet.
View Article and Find Full Text PDFDiabetes Obes Metab
January 2025
Eli Lilly and Company, Indianapolis, Indiana, USA.
Aims: To explore the relationship between weight loss and insulin sensitivity in response to tirzepatide or semaglutide.
Materials And Methods: We conducted a post hoc exploratory analysis of a 28-week, double-blind, randomized trial in people with type 2 diabetes treated with metformin, randomized to tirzepatide 15 mg, semaglutide 1 mg or placebo. We evaluated the relationship between change in body weight and change in insulin sensitivity determined from hyperinsulinemic euglycemic clamp (M value), or from mixed-meal tolerance testing (Matsuda index).
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