Laser usage in veterinary dermatology has increased in popularity over the last several decades. Carbon dioxide (CO) laser is the leading modality in surgical laser for veterinary dermatology because of its unmatched performance with soft tissue, particularly the skin. This laser cuts and coagulates tissue via the photothermal effect of laser energy when interacting with soft tissues with high water content, such as skin. CO laser modality has many indications for the diagnosis and treatment of dermatologic conditions in animals. This article will review the basics of CO laser and how to utilize it in veterinary dermatology.
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http://dx.doi.org/10.1016/j.cvsm.2024.11.005 | DOI Listing |
JID Innov
January 2025
Centre for Stem Cell and Regenerative Medicince, King's College London, London, United Kingdom.
Penile intraepithelial neoplasia (PeIN) and penile squamous cell carcinoma (PeSCC) are both thought to be associated with male genital lichen sclerosus and human papillomavirus (HPV) infection through dichotomous pathways: (i) undifferentiated PeIN and warty/basaloid PeSCC are thought to be HPV related, whereas (ii) differentiated PeIN and usual PeSCC are considered HPV independent. Tissue arrays were constructed from male genital lichen sclerosus, undifferentiated and differentiated PeIN, usual-type PeSCC, and unaffected tissues. Staining for p16 and for high-risk and low-risk HPV subtypes through RNAscope was performed.
View Article and Find Full Text PDFVet Dermatol
January 2025
Department of Veterinary Medicine, University of Perugia, Perugia, Italy.
Background: In humans, the presence of an even distribution of melanocytes within the epidermal basal layer allows for uniform pigmentation in healthy and young individuals. Moreover, despite high variability in skin colours and tones, interindividual melanocyte density variability is low. However, dogs display a high intraindividual pigmentary variability in different anatomical areas.
View Article and Find Full Text PDFVet Dermatol
January 2025
Elanco Animal Health, Greenfield, Indiana, USA.
Background: Janus kinase inhibitors (JAKi) have been shown to reduce pruritus and improve associated inflammatory skin lesions in canine atopic dermatitis (cAD).
Objective: To evaluate the efficacy and safety of ilunocitinib, in comparison to oclacitinib, for the control of cAD in a randomised, blinded trial.
Animals: Three-hundred-and-thirty-eight dogs with cAD.
Vet Clin North Am Small Anim Pract
January 2025
Pathobiology University of Pennsylvania, School of Veterinary Medicine, 3900 Delancey Street, MJR VHUP, Room 4040, Philadelphia, PA 19104, USA.
Nasal planum dermatoses in dogs can be infectious, immune-mediated, allergic, neoplastic, and metabolic in nature. Recognizing key lesions and features and knowing how and when to biopsy can help distinguish between similar diseases. The focus of this article is to review the most commonly encountered nasal planum dermatoses in dogs and to enable the veterinary practitioner to recognize and differentiate between them to obtain a diagnosis.
View Article and Find Full Text PDFSci Rep
January 2025
Foot and Ankle Research and Innovation Lab (FARIL), Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Tendon injuries present significant medical, social, and economic challenges globally. Despite advancements in tendon injury repair techniques, outcomes remain suboptimal due to inferior tissue quality and functionality. Tissue engineering offers a promising avenue for tendon regeneration, with biocompatible scaffolds playing a crucial role.
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