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Correction to: Autophagy-related gene BECN1 single nucleotide polymorphisms in diseases.
Mol Cell Biochem
January 2025
Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, Punjab, 143 005, India.
Selenium triggers AMPK-mTOR pathway to modulate autophagy related to oxidative stress of sheep Leydig cells.
Reprod Biol
November 2024
College of Animal Science, Shanxi Agricultural University, Taigu 030801, PR China; Laboratory of Animal Reproductive biotechnology, Shanxi Agricultural University, Taigu 030801, PR China. Electronic address:
The objective of this study was to investigate the effect of oxidative stress induced by excessive Se on autophagy of sheep Leydig cells and its underlying mechanism. Leydig cells isolated from the testis of 8-month-old sheep were purified using a discontinuous Percoll density gradient. Cells were divided into four treatment groups (0, 2.
View Article and Find Full Text PDFTMEM232 is required for the formation of sperm flagellum and male fertility in mice.
Cell Death Dis
November 2024
School of Life Science, Anhui Medical University, Hefei, 230022, China.
Asthenoteratozoospermia is a major cause of male infertility. Thus far, the identified related genes can explain only a small share of asthenoteratozoospermia cases, suggesting the involvement of other genes. The transmembrane protein TMEM232 is highly expressed in mouse testes.
View Article and Find Full Text PDF[Corrigendum] MicroRNA‑378 enhances migration and invasion in cervical cancer by directly targeting autophagy‑related protein 12.
Mol Med Rep
January 2025
Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China.
Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that, for the cell migration and invasion assay experiments shown in Fig. 2 on p. 6322, the 'HeLa/miR‑378 inhibitor' panels in Fig.
View Article and Find Full Text PDFThioredoxin C of Streptococcus suis serotype 2 contributes to virulence by inducing antioxidative stress and inhibiting autophagy via the MSR1/PI3K-Akt-mTOR pathway in macrophages.
Vet Microbiol
November 2024
Department of Endocrinology, Shenzhen Longhua District Central Hospital, Shenzhen 518110, China; School of Life Science and Engineering, Foshan University, Guangdong 528225, China. Electronic address:
The thioredoxin (Trx) system plays a vital role in protecting against oxidative stress and ensures correct disulfide bonding to maintain protein function. Our previous research demonstrated that TrxA of Streptococcus suis Serotype 2 (SS2), a clinical strain from the lung of a diseased pig, contributes to virulence but is not involved in antioxidative stress. In this study, we identified another gene in the Trx family, TrxC, which encodes a protein of 104 amino acids with a CGDC active motif and 22.
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