Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s13312-025-3365-7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Glycerol-3-Phosphate Dehydrogenase 1 Deficiency: A Rare Cause of Fatty Liver Disease in Children.
Indian Pediatr
January 2025
Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Glycerol-3-phosphate contributes to the increase in FGF23 production in chronic kidney disease.
Am J Physiol Renal Physiol
December 2024
Nephrology Division, Department of Medicine, Massachusetts General Hospital, Boston, MA , USAXXXX, XXX.
Why fibroblast growth factor 23 (FGF23) levels increase markedly in chronic kidney disease (CKD) is unknown. Recently, we found that phosphate stimulates renal production of glycerol-3-phosphate (G-3-P), which circulates to bone to trigger FGF23 production. To assess the impact of G-3-P on FGF23 production in CKD, we compared the effect of adenine-induced CKD in mice deficient in glycerol-3-phosphate dehydrogenase 1 (Gpd1), an enzyme that synthesizes G-3-P, along with wild-type littermates.
View Article and Find Full Text PDFFerroptosis: when metabolism meets cell death.
Physiol Rev
December 2024
Institute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
We present here a comprehensive update on recent advancements in the field of ferroptosis, with a particular emphasis on its metabolic underpinnings and physiological impacts. After briefly introducing landmark studies that have helped to shape the concept of ferroptosis as a distinct form of cell death, we critically evaluate the key metabolic determinants involved in its regulation. These include the metabolism of essential trace elements such as selenium and iron; amino acids such as cyst(e)ine, methionine, glutamine/glutamate and tryptophan; and carbohydrates, covering glycolysis, the citric acid cycle, the electron transport chain and the pentose phosphate pathway.
View Article and Find Full Text PDFMorpho-cultural and molecular variability of causing Stemphylium leaf blight in tropical onions.
Heliyon
October 2024
Division of Vegetable Science, ICAR-Indian Agricultural Research Institute, Delhi, 110012, India.
The cultural, morphological, and molecular variations among 22 isolates of (Wallr.) E. Simmons, collected from different locations, was carried out.
View Article and Find Full Text PDFEnzyme-constrained Metabolic Model of Identified Glycerol-3-phosphate Dehydrogenase as an Alternate Electron Sink.
bioRxiv
November 2024
Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln.
, the causative agent of syphilis, poses a significant global health threat. Its strict intracellular lifestyle and challenges in cultivation have impeded detailed metabolic characterization. In this study, we present iTP251, the first genome-scale metabolic model of , reconstructed and extensively curated to capture its unique metabolic features.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!