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Malaria burden and associated risk factors among malaria suspected patients attending health facilities in Kaffa zone, Southwest Ethiopia.
Malar J
December 2024
College of Natural Sciences, Department of Biology, Jimma University, Jimma, Ethiopia.
Background: Ethiopia has been progressing very well in controlling malaria in the past few years. However, shortly after the COVID-19 pandemic, an unpredictable malaria resurgence was observed in almost all malaria-endemic areas of the country, although the exact cause of which has not yet been identified. Therefore, this study aimed to investigate malaria burden and associated risk factors in one of the endemic zones of Ethiopia.
View Article and Find Full Text PDFMalaria remains a major global public health issue, demanding significant resources from governments, health organizations, and international organizations toward its elimination as an endemic disease. In 2016, Sri Lanka achieved the remarkable feat of being declared "malaria free" by the World Health Organisation (WHO), after over a century of indigenous disease. To identify significant lessons of global importance in eliminating endemic malaria by reviewing literature on Sri Lanka's successful elimination campaign.
View Article and Find Full Text PDFThe issue of climate change and the spread of tropical diseases in Europe and Italy: vector biology, disease transmission, genome-based monitoring and public health implications.
Infect Dis (Lond)
December 2024
Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Background: Climate change significantly influences the distribution and severity of tropical diseases. Rising temperatures, changing precipitation patterns, and extreme weather events are transforming the habitats of vectors like mosquitoes and ticks, promoting their proliferation and geographic spread. These changes have facilitated the resurgence of diseases such as malaria, dengue, and chikungunya fever in previously unaffected areas, including parts of Europe and Italy.
View Article and Find Full Text PDFPost-treatment duration of positivity for standard and ultra-sensitive Plasmodium falciparum antigen-based rapid diagnostic tests, a cohort study from a low-endemic setting in Namibia.
EBioMedicine
January 2025
Malaria Elimination Initiative, Global Health Group, University of California, San Francisco (UCSF), San Francisco 94158, USA; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75390, USA; Department of Pediatrics, UCSF Benioff Children's Hospital, San Francisco 94158, USA; Department of Epidemiology and Biostatistics, UCSF, San Francisco 94158, USA. Electronic address:
Article Synopsis
- - The study investigated how long malaria rapid diagnostic tests (RDT) and ultra-sensitive RDT (uRDT) remained positive after treatment in a low transmission area in Namibia, finding an average positivity duration of 42 days for RDT and 67 days for uRDT.
- - Factors such as younger age, higher initial parasite density, and persistent parasitemia were linked to longer test positivity, indicating that the usual explanations for lingering positive results, like drug resistance, did not apply.
- - These prolonged positivity durations highlight challenges in using RDTs and uRDTs for accurately identifying current infections in low transmission settings, as they might reflect residual parasite DNA rather than active infection.
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