Objectives: To assess the prevalence and associated factors of hearing loss in Ethiopia, considering socioeconomic conditions, regional variations and age-related impacts.
Design: Nationwide cross-sectional survey.
Setting: Data were collected from 2 February to 10 June 2023, covering all regions of Ethiopia except Tigray (due to security concerns).
Participants: A sample of 3000 households and 7061 individuals aged 5 years and above was selected using a multistage sampling procedure. Eligible participants had resided in the area for at least 6 months. Exclusions included visitors, critically ill individuals and those with communication difficulties.
Outcome Measures: Hearing loss was defined as an average hearing threshold >20 dB in the better ear at frequencies of 0.5 kHz, 1 kHz, 2 kHz and 4 kHz, measured using pure-tone audiometry. Logistic regression analysis was performed to determine factors associated with hearing loss.
Results: The overall prevalence of hearing loss among individuals aged 5+ years was 18.4%. The prevalence was 8.1% among children aged 5-14 years and 73.7% among adults aged 60+ years. Factors significantly associated with hearing loss included being over 60 years old (adjusted OR (AOR)=51.41; 95% CI 36.95, 71.53), having no formal education (AOR=2.12; 95% CI 1.47, 3.08), ear discharge (AOR=3.01; 95% CI 2.07, 4.38), wax presence (AOR=1.92; 95% CI 1.53, 2.40), and tympanic membrane abnormality (AOR=17.17; 95% CI 12.27, 24.02). Participants from the Harari (AOR=3.25; 95% CI 1.85, 5.72) and Somali (AOR=2.37; 95% CI 1.49, 3.77) regions were more likely to experience hearing loss compared with those from other regions.
Conclusions: Hearing loss is highly prevalent in Ethiopia, influenced by both modifiable and non-modifiable factors. Regional disparities in hearing loss suggest a need for targeted interventions. Evidence-based policies and strategies are essential to reduce ear diseases, improve hearing care services, and address disparities in hearing health across regions.
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http://dx.doi.org/10.1136/bmjopen-2024-086288 | DOI Listing |
Hum Genet
January 2025
Division of Hearing and Balance Research, National Institute of Sensory Organs, NHO Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-Ku, Tokyo, 152-8902, Japan.
There are hundreds of rare syndromic diseases involving hearing loss, many of which are not targeted for clinical genetic testing. We systematically explored the genetic causes of undiagnosed syndromic hearing loss using a combination of whole exome sequencing (WES) and a phenotype similarity search system called PubCaseFinder. Fifty-five families with syndromic hearing loss of unknown cause were analyzed using WES after prescreening of several deafness genes depending on patient clinical features.
View Article and Find Full Text PDFArch Dermatol Res
January 2025
Tianjin Medical University, Tianjin, 300102, China.
Objective: This study aims to investigate the genetic link between psoriasis and sudden sensorineural hearing loss (SSNHL).
Methods: From a genetic standpoint, this study further highlighted the connection between psoriasis and SSNHL. Single nucleotide polymorphisms (SNPs) connected to SSNHL could be found using a genome-wide association study from the IEU OpenGWAS project website.
BMC Neurol
January 2025
Faculty of Medicine, Department of Neurology, Al-Quds University, Jerusalem, Palestine.
Background: Vanishing white matter disease (VWMD) is a rare autosomal recessive leukoencephalopathy. It is typified by a gradual loss of white matter in the brain and spinal cord, which results in impairments in vision and hearing, cerebellar ataxia, muscular weakness, stiffness, seizures, and dysarthria cogitative decline. Many reports involve minors.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Audiovestibular Medicine, St George's Hospital, London, UK.
A toddler presented to audiovestibular medicine with mild bilateral, sensorineural hearing loss identified via the Newborn Hearing Screening Programme. This report focuses on the early clinical assessment and aetiological investigation which prompted testing for metabolic disease and highlights the parents' perspective. Early investigation led to a relatively early diagnosis of mucopolysaccharidosis (MPS) type IIIA: Sanfilippo disease which enabled the family to access a novel treatment option which otherwise would not have been possible.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Haematology, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK
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