In this issue of Structure, Ma et al. apply the artificial intelligence system AlphaFold2, which was designed to predict three-dimensional protein structures from amino acid sequences with atomic accuracy, to model the conformal dynamics of the prokaryotic TpCorC and human CNNM2 and CNNM4 transporters, providing mechanistic insight into how sodium drives magnesium efflux.
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| http://dx.doi.org/10.1016/j.str.2024.12.006 | DOI Listing |
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