Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Background: Pomegranate peel extract (PPE) is rich in polyphenols, notably punicalagin and ellagic acid, but is sensitive to environmental degradation and has low bioavailability. Microencapsulation can enhance PPE stability and bioaccessibility, making it suitable for functional foods like jelly gummies (JG). JG containing microencapsulated PPE (MPPE) have not been studied.
Objective: To characterize a JG prototype incorporating PPE or MPPE and compare the bioaccessibility of total polyphenols (TP), punicalagin, and ellagic acid after a simulated in vitro digestion.
Methods: PPE-JG and MPPE-JG prototypes were evaluated for physical, sensory, and chemical properties. The bioaccessibility of the main bioactive compounds was analyzed using the INFOGEST digestion protocol.
Results: Bioaccessibility was significantly higher for MPPE-JG compared to PPE-JG for TP (164.1 ± 6.0 vs. 100.0 ± 5.8 %, respectively) and punicalagin (173.4 ± 4.4 vs. 106.5 ± 4.2 %, respectively). MPPE-JG exhibited enhanced bioaccessibility, suggesting MPPE as a viable, functional ingredient in healthy gummies.
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Source |
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http://dx.doi.org/10.1016/j.foodchem.2024.142611 | DOI Listing |
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