Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1113/JP288185 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metabolite mysteries: Decoding age-related muscle fatigue mechanisms at the myofibrillar level.
J Physiol
January 2025
Muscle Health Research Centre, School of Kinesiology & Health Science, Faculty of Health, York University, Toronto, ON, Canada.
The Isodon serra genome sheds light on tanshinone biosynthesis and reveals the recursive karyotype evolutionary histories within Lamiales.
Plant J
November 2024
School of Pharmacy, Lanzhou University, Lanzhou, 730000, China.
Lamiales is one of the largest orders of angiosperms with a complex evolutionary history and plays a significant role in human life. However, the polyploidization and chromosome evolution histories within this group remain in mystery. Among Lamiales, Isodon serra (Maxim.
View Article and Find Full Text PDFDisentangling the molecular mystery of tumour-microbiota interactions: Microbial metabolites.
Clin Transl Med
November 2024
State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, PR China.
Article Synopsis
- The microbiota significantly influences cancer initiation and progression, with microbial metabolites connecting these two areas, though the detailed molecular mechanisms are still unclear.* -
- Various mechanisms, such as disrupting cell signaling and reshaping the tumor immune environment, are important in understanding how tumours develop and resist therapy.* -
- Current research highlights the critical roles of microbial metabolites in cancer, but challenges like the need for better quantification methods and integrating different research approaches still remain.*
Advances and challenges in non-targeted analysis: An insight into sample preparation and detection by liquid chromatography-mass spectrometry.
J Chromatogr A
November 2024
National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), An Institute of National Importance, Government of India, Palaj, Gandhinagar, Gujarat 382355, India. Electronic address:
Article Synopsis
- - Non-targeted analysis is an advanced method used to identify unknown impurities and pollutants in pharmaceutical, biological, and environmental samples, overcoming the limitations of traditional targeted analysis which can only quantify known chemicals.
- - This analytical approach employs high-end techniques like high-resolution mass spectrometry and liquid chromatography mass spectrometry, allowing researchers to uncover unidentified metabolites and compounds in complex mixtures.
- - The review covers the latest advancements in non-targeted analysis, including sample collection and preparation processes, benefits and limitations of the method, as well as the importance of bioinformatics in managing large datasets for effective interpretation.
Pangolin scales as adaptations for innate immunity against pathogens.
BMC Biol
October 2024
College of Science, Mathematics and Technology, Wenzhou-Kean University, 88 Daxue Road, Ouhai, Wenzhou, Zhejiang Province, 325060, China.
Background: Pangolins are the only mammals that have overlapping scales covering most of their bodies, and they play a crucial role in the ecosystem, biological research, and human health and disease. Previous studies indicated pangolin scale might provide an important mechanical defense to themselves. The origin and exact functions of this unique trait remain a mystery.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!