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Preventing disease progression in schizophrenia: What are we waiting for.
J Psychiatr Res
December 2024
Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.
Despite research advances and progress in health care, schizophrenia remains a debilitating and costly disease. Onset occurs typically during youth and can lead to a relapsing and ultimately chronic course with persistent symptoms and functional impairment if not promptly and properly treated. Consequently, over time, schizophrenia causes substantial distress and disability for patients, their families and accrues to a collective burden to society.
View Article and Find Full Text PDFEmploying a Phased, Interdisciplinary Approach Across Healthcare and School Settings: mHealth Adaptations for Youth with Autism Spectrum Disorder At-Risk of Experiencing Obesity.
J Autism Dev Disord
January 2025
Department of Public Health Sciences, Clemson University, Clemson, SC, USA.
Youth with autism spectrum disorder (ASD) are at nearly twice the risk of experiencing obesity, compared to youth without ASD. Wellness Education to Create Healthy habits and Actions to Thrive (WE CHAT) is a novel chatbot that engages participants to enhance primary care delivery and associated care coordination services through mobile health (mHealth) technology focused on social determinants of health (SDOH) and social-emotional health. This study examines multiple perspectives regarding the development and implementation of innovative mHealth technology among youth with ASD.
View Article and Find Full Text PDFObjective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.
View Article and Find Full Text PDFNetwork intervention analysis to assess the trajectory of change and intervention effects associated with the use of self-control training for ego depletion aftereffects.
BMC Psychol
January 2025
Department of Medical Psychology, Air Force Medical University, Xi'an, China.
Purpose: The purpose of this study was to use the advanced technique of Network Intervention Analysis (NIA) to investigate the trajectory of symptom change associated with the effects of self-control training on youth university students' chronic ego depletion aftereffects.
Methods: The nine nodes of chronic ego depletion aftereffects and integrated self-control training were taken as nodes in the network and analyzed using NIA. Networks were computed at the baseline, at the end of treatment, at 1-, 3-, 6-, 9- and 12-month follow up.
Cross-species single-nucleus analysis reveals the potential role of whole-genome duplication in the evolution of maize flower development.
BMC Genomics
January 2025
Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agriculture Sciences in Weifang, Weifang, Shandong, 261325, China.
Background: The evolution and development of flowers are biologically essential and of broad interest. Maize and sorghum have similar morphologies and phylogeny while harboring different inflorescence architecture. The difference in flower architecture between these two species is likely due to spatiotemporal gene expression regulation, and they are a good model for researching the evolution of flower development.
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